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Updated: Aug 19, 2025
Retzius-Sparing Robot-Assisted Radical Prostatectomy
Published on: May 19, 2022
Variation in patient reported outcomes following radical prostatectomy: A bi-national registry-based study
Michael E O'Callaghan1, Matthew J Roberts2, Kim L Moretti3
1Urology Unit, Flinders Medical Centre, Adelaide, South Australia, Australia; College of Medicine and Public Health, Flinders University, Adelaide, South Australia, Australia; Discipline of Medicine, University of Adelaide, Adelaide, South Australia, Australia.
Radical prostatectomy outcomes show significant variation in urinary incontinence and sexual function 12 months post-surgery. Patient age and surgeon volume impact results, highlighting the need to address variability in prostate cancer treatment.
Area of Science:
- Urology
- Oncology
- Health Services Research
Background:
- Radical prostatectomy (RP) is a primary treatment for localized prostate cancer.
- Post-RP sequelae include urinary incontinence and sexual dysfunction.
- Population-wide outcomes data are crucial for understanding treatment impact.
Purpose of the Study:
- To report 12-month urinary incontinence and sexual function outcomes after RP.
- To quantify and explore factors associated with outcome variations.
- To identify patient and clinician factors influencing functional recovery.
Main Methods:
- Utilized the Prostate Cancer Outcomes Registry of Australia and New Zealand (PCOR-ANZ).
- Analyzed data from 13,083 men undergoing RP between 2016-2020.
- Assessed urinary incontinence and sexual function using EPIC-26 scores and bother levels; employed multivariable regression models.
Main Results:
- Mean incontinence score was 76/100 (9.2% major bother); mean sexual function score was 29/100 (46% major bother).
- Age at surgery and clinician surgical volume were key predictors of functional outcomes.
- Significant variation in outcomes was observed, even within similar clinician volume categories.
Conclusions:
- Considerable variation exists in 12-month functional outcomes post-RP.
- Both patient and clinician factors contribute to outcome disparities.
- Further research is needed to identify and address unmeasured confounding factors.
