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Author Spotlight: A Pseudotype Virus System for Assessing Omicron Subvariants and Neutralizing Antibodies in SARS-CoV-2 Research
Published on: September 8, 2023
Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years
Christine Durier1, Laetitia Ninove2, Maeva Lefebvre3
1INSERM US19, Villejuif, France. christine.durier@inserm.fr.
Abstract:
Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65-84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost.
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