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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
Published on: June 13, 2021
COVID-19 and Pregnancy
Selia Chowdhury1, Mehedi Hasan Bappy2, Shreeya Desai3
1Dhaka Medical College, Dhaka, Bangladesh.
Insights
Pregnant women face higher risks from COVID-19. Vaccines are safe and effective, protecting both mothers and babies from severe illness and death during pregnancy and childbirth.
Area of Science:
- Obstetrics and Gynecology
- Infectious Diseases
- Neonatal Medicine
Background:
- COVID-19 poses significant risks to pregnant individuals, increasing their likelihood of severe illness compared to non-pregnant individuals.
- Emerging research investigates the multifaceted impact of SARS-CoV-2 (the virus causing COVID-19) on maternal health, fetal development, and neonatal outcomes.
- Understanding these effects is crucial for developing targeted interventions and ensuring optimal care during the pandemic.
Purpose of the Study:
- To comprehensively review the influence of COVID-19 on pregnancy, including its pathophysiology.
- To examine the effects of SARS-CoV-2 on the placenta and neonates.
- To discuss maternal and perinatal outcomes, vaccination efficacy, treatment options, and labor/delivery guidelines.
Main Methods:
- Literature review of available scientific evidence on COVID-19 in pregnancy.
- Analysis of reported cases and scientific studies concerning maternal and neonatal health.
- Synthesis of data on vaccine safety, treatment protocols, and pandemic-specific childbirth guidelines.
Main Results:
- Pregnant women are at an increased risk for severe COVID-19 illness.
- While rare, fetal transmission of SARS-CoV-2 can occur; newborns are susceptible to postnatal exposure.
- COVID-19 vaccines are demonstrated as safe and highly effective in preventing infection, severe disease, and death in pregnant individuals and their infants.
Conclusions:
- COVID-19 vaccination is a critical tool for safeguarding maternal and fetal health during the pandemic.
- Adherence to specific labor and delivery guidelines is essential for safer childbirth.
- Continued research and evidence-based practices are vital for managing COVID-19's impact on pregnancy.
Abstract:
It is of greatest concern how COVID-19 is affecting pregnancy, mothers, and babies. Scientists are studying the impact of COVID-19 on pregnant women and babies and are understanding a little more every day. Reports show that there is an increased risk in pregnant women compared to nonpregnant women to get more serious illness due to COVID-19. Researchers are also investigating COVID-19 and its potential impact on a fetus. There are exceedingly rare cases of COVID-19 transmission to the fetus, and newborns can pick up COVID-19 when exposed. Vaccines are proved to be safe for pregnant women and help prevent both mother and the fetus from getting COVID-19 and are also highly effective to prevent COVID-19 infection, critical sickness, and fatalities in general. There are specific guidelines for labor and delivery during the COVID-19 pandemic which are to be imposed and followed to achieve safer and healthier childbirth. In this article, the overall influence of COVID-19 in pregnancy, its pathophysiology, effects on placenta and neonates, maternal and perinatal features and outcomes, the role of vaccination, available treatment options, and the guidelines to be followed during the pandemic are discussed based on the available scientific evidence.
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