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Viruses are unique biological entities that blur the boundary between living and non-living systems. Although they lack cellular structure and metabolic processes, they can exhibit characteristics of life when infecting a host. Their defining feature is a nucleic acid core, composed of either DNA or RNA, encapsulated within a protein coat called a capsid. This simple structure allows them to invade host cells and use their machinery for replication efficiently.Viral Structure and...
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Related Experiment Video

Updated: Aug 19, 2025

Arbovirus Infections As Screening Tools for the Identification of Viral Immunomodulators and Host Antiviral Factors
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A virus changed my life.

Renato J Aguilera1

  • 1Biological Sciences and Border Biomedical Research Center, University of Texas at El Paso, El Paso, TX 79968-0519.

Molecular Biology of the Cell
|November 28, 2022
PubMed
Summary

This research honors Dr. Ernest Everett Just by recognizing a commitment to advancing biomedical careers for Persons Excluded due to Ethnicity or Race (PEERS). The work involves training underrepresented students and discovering novel anticancer agents.

Area of Science:

  • Biomedical Sciences
  • Cancer Research
  • Immunology

Background:

  • The E. E. Just Award honors Dr. Ernest Everett Just, a pioneering African-American cell biologist.
  • The award recognizes a commitment to supporting Persons Excluded due to Ethnicity or Race (PEERS) in science.
  • The recipient has a history of training underrepresented students in scientific careers.

Purpose of the Study:

  • To highlight the importance of diversity and inclusion in science.
  • To showcase a career dedicated to mentoring underrepresented groups.
  • To present research focused on the discovery of novel anticancer agents.

Main Methods:

  • Early research involved molecular immunology, focusing on antigen-receptor gene recombination.
  • Characterization of nuclear factors in recombination and transcriptional regulation.

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  • Recent research focuses on discovering and evaluating novel anticancer agents.

    • Main Results:

    • Significant contributions to understanding gene recombination in immunology.
    • Development of expertise in identifying potential cancer treatments.
    • Successful mentorship of numerous underrepresented students pursuing scientific careers.

    Conclusions:

    • The commitment to supporting PEERS is crucial for scientific advancement.
    • Continued research into novel anticancer agents holds promise for cancer treatment.
    • The legacy of Dr. E. E. Just inspires efforts to overcome systemic exclusion in science.