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Related Concept Videos

Anxiety: Overview01:18

Anxiety: Overview

332
Anxiety is a common mental disorder featuring excessive worry, fear, and apprehension, significantly affecting daily life. People with anxiety disorders experience persistent and intense anxiety, interrupting their everyday functioning.
Individuals with anxiety often experience a range of physical and emotional symptoms, including sweating, trembling, tachycardia, and disturbances in sleep patterns. These symptoms vary in intensity and frequency but are generally disruptive and distressing.
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Generalized Anxiety Disorder01:30

Generalized Anxiety Disorder

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Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
179
Social Anxiety Disorder01:28

Social Anxiety Disorder

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Social anxiety disorder, also known as social phobia, is characterized by an intense fear of social situations where one might face humiliation, rejection, embarrassment, or negative evaluation. This disorder leads individuals to avoid activities like casual conversations, public speaking, or seemingly simple tasks such as eating, signing documents, or swimming, in public settings. Its impact extends beyond discomfort, often significantly interfering with daily functioning and quality of life.
70
Panic Disorder01:27

Panic Disorder

163
Panic disorder is an anxiety disorder characterized by recurrent and sudden minutes-long episodes of intense fear, known as panic attacks. These attacks may feel like heart attacks and often happen without warning or a specific cause. They can include symptoms such as rapid heart rate, shortness of breath, chest pain, trembling, sweating, dizziness, and a sense of helplessness. During a panic attack, individuals may feel as though they are experiencing a heart attack or are in a...
163
Stress and Mental Health01:30

Stress and Mental Health

196
Chronic stress profoundly affects mental health, significantly influencing mood, behavior, and overall quality of life. Research closely links chronic stress with mental health conditions such as depression, anxiety, and substance use disorders. Ongoing exposure to stress can lead to physiological and psychological changes, initiating a cycle of emotional distress and maladaptive coping mechanisms.
Individuals with depression often experience challenges in both their personal and professional...
196
Obsessive-Compulsive Disorder01:28

Obsessive-Compulsive Disorder

183
Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
183

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A New Method for Inducing a Depression-Like Behavior in Rats
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Factors associated with anxiety disorder comorbidity.

Molly R Davies1, Kiran Glen1, Jessica Mundy1

  • 1Institute of Psychiatry, Psychology and Neuroscience, King's College London, Denmark Hill, Camberwell, London, UK; National Institute for Health and Care Research (NIHR) Biomedical Research Centre, South London and Maudsley Hospital, London, UK.

Journal of Affective Disorders
|November 28, 2022
PubMed
Summary
This summary is machine-generated.

Anxiety comorbidity, including anxiety-anxiety and anxiety-major depressive disorder (MDD), presents severe symptoms. Early onset anxiety influences outcomes more than early onset MDD, highlighting the need for further research.

Keywords:
Affective disordersAnxiety disordersComorbidityDepressive disordersPolygenic risk score

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Epidemiology

Background:

  • Anxiety and depressive disorders frequently co-occur, influencing clinical outcomes.
  • Research on anxiety-anxiety comorbidity is limited.
  • Understanding the temporal sequence of anxiety and major depressive disorder (MDD) is crucial.

Purpose of the Study:

  • To investigate factors associated with anxiety-anxiety comorbidity.
  • To examine the temporal sequence of anxiety and MDD onset.
  • To compare clinical profiles of different anxiety and depressive disorder comorbidities.

Main Methods:

  • Utilized online self-report data from UK cohorts (N=38,775).
  • Employed logistic regression to compare sociodemographic, trauma, and clinical factors.
  • Assessed familial risk using self-reported history and genotype data.

Main Results:

  • Anxiety-anxiety and anxiety-MDD showed higher diagnosis rates, earlier onset, and greater recurrence than single anxiety.
  • Anxiety-MDD exhibited greater clinical severity than MDD alone.
  • Anxiety-first MDD had earlier onset and greater severity than MDD-first anxiety-MDD.

Conclusions:

  • Anxiety-anxiety comorbidity shares severity with anxiety-MDD but has distinct features.
  • Early onset anxiety in anxiety-MDD is linked to greater severity.
  • Anxiety disorders and their comorbidities require further research and clinical attention.