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Updated: Aug 19, 2025

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Automated Segmentation of Cortical Grey Matter from T1-Weighted MRI Images
Published on: January 7, 2019
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Regional Gray Matter Volume Is Associated with Growth Mindset: A Voxel-Based Morphometry Study
Xiaoyu Jia1, Lei Hao1, Li He2
1College of Teacher Education, Southwest University, Chongqing, China.
Neuroscience
|November 28, 2022
Summary
Beliefs about intelligence influence motivation and achievement. This study found a link between a growth mindset and greater gray matter volume in the medial orbitofrontal cortex, a brain region involved in reward processing.
Area of Science:
- Neuroscience
- Cognitive Psychology
- Psychology
Background:
- A growth mindset, the belief that intelligence can be developed, is crucial for motivation and achievement.
- The neural underpinnings of a growth mindset remain largely unexplored.
- Understanding the brain mechanisms associated with a growth mindset can provide insights into learning and cognitive development.
Purpose of the Study:
- To investigate the relationship between growth mindset and brain structure, specifically gray matter volume (GMV).
- To identify specific brain regions associated with growth mindset beliefs in healthy adults.
Main Methods:
- Utilized voxel-based morphometry (VBM) on anatomical magnetic resonance imaging (MRI) scans.
- Administered the Growth Mindset Inventory and an intelligence test to participants.
- Analyzed whole-brain correlations between growth mindset scores and regional GMV in a sample of 389 healthy adults (114 men, 275 women).
Main Results:
- A significant positive correlation was observed between higher growth mindset scores and increased GMV in the medial orbitofrontal cortex (mOFC).
- This association remained significant after controlling for age, sex, total intracranial volume, and intelligence quotient.
- The mOFC is a key region implicated in reward processing.
Conclusions:
- The findings suggest a neural basis for the growth mindset, linking it to the brain's reward system via the mOFC.
- This supports the social-cognitive theory of motivation, highlighting the role of reward in fostering a growth mindset.
- Future research could explore interventions targeting the mOFC to cultivate a growth mindset.
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