Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cystic Fibrosis: Management01:24

Cystic Fibrosis: Management

210
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
210
Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

16
Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
16
Chronic Obstructive Pulmonary Disease-V: Management01:29

Chronic Obstructive Pulmonary Disease-V: Management

2.7K
Managing Chronic Obstructive Pulmonary Disease (COPD) involves a multifaceted approach to reduce symptoms, prevent exacerbations, improve overall health status, and slow disease progression. Key strategies include lifestyle modifications, pharmacotherapy, supportive therapies, and, in some cases, surgery. Here is an overview of the primary COPD management strategies:
Smoking Cessation
2.7K
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

25
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
25
Mitral Regurgitation III: Medical Management01:25

Mitral Regurgitation III: Medical Management

25
Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...
25
Mitral Stenosis IV: Nursing Management01:27

Mitral Stenosis IV: Nursing Management

26
A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...
26

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postnatally acquired cytomegalovirus infection in preterm infants: an update on diagnosis, management and outcomes.

Archives of disease in childhood. Fetal and neonatal edition·2026
Same author

Dolutegravir as First- or Second-line Treatment for Children With HIV: 240-Week Follow-up of the ODYSSEY Randomized Trial.

Open forum infectious diseases·2026
Same author

Duration of Postnatal HIV Prophylaxis: How Long Is Long Enough?

The Pediatric infectious disease journal·2026
Same author

National Cross-Sectional Study Assessing the Positivity Rate and Clinical Manifestations of Human Bocavirus Respiratory Infections Among Hospitalized Children Under 5 Years of Age in Jordan.

Pathogens (Basel, Switzerland)·2026
Same author

From evidence gaps to action: why Delphi consensus has become indispensable in perinatal medicine.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2026
Same author

Bias in AI models for fetal cardiac screening: the consequences of training predominantly on normal anatomy.

Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology·2026

Related Experiment Video

Updated: Aug 19, 2025

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

15.1K

Managing challenges in congenital CMV: current thinking.

Christine E Jones1,2, Heather Bailey3, Alasdair Bamford4,5

  • 1Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK c.e.jones@soton.ac.uk.

Archives of Disease in Childhood
|November 28, 2022
PubMed
Summary
This summary is machine-generated.

Congenital cytomegalovirus (CMV) infection is common and can cause lifelong issues in infants. Early diagnosis and treatment are crucial for better outcomes, yet awareness remains low among the public and healthcare providers.

Keywords:
Infectious Disease MedicineNeonatology

More Related Videos

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

19.7K
Automated Cell Enrichment of Cytomegalovirus-specific T cells for Clinical Applications using the Cytokine-capture System
10:24

Automated Cell Enrichment of Cytomegalovirus-specific T cells for Clinical Applications using the Cytokine-capture System

Published on: October 5, 2015

12.5K

Related Experiment Videos

Last Updated: Aug 19, 2025

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates
05:53

Use of In vivo Imaging to Monitor the Progression of Experimental Mouse Cytomegalovirus Infection in Neonates

Published on: July 6, 2013

15.1K
Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain
05:51

Intracerebroventricular and Intravascular Injection of Viral Particles and Fluorescent Microbeads into the Neonatal Brain

Published on: July 24, 2016

19.7K
Automated Cell Enrichment of Cytomegalovirus-specific T cells for Clinical Applications using the Cytokine-capture System
10:24

Automated Cell Enrichment of Cytomegalovirus-specific T cells for Clinical Applications using the Cytokine-capture System

Published on: October 5, 2015

12.5K

Area of Science:

  • Pediatrics
  • Infectious Diseases
  • Public Health

Background:

  • Congenital human cytomegalovirus (CMV) is the most frequent congenital infection, impacting approximately 1 in 200 infants in high-income countries.
  • This infection can lead to severe, lifelong consequences in up to 25% of affected children, including neurodevelopmental disabilities and sensorineural hearing loss.
  • Despite its prevalence and potential severity, congenital CMV remains poorly recognized by pregnant women, families, and healthcare professionals.

Purpose of the Study:

  • To highlight the significance of timely diagnosis of CMV infection during pregnancy for potential treatment with valaciclovir.
  • To emphasize the importance of recognizing congenital CMV symptoms for prompt neonatal testing within 21 days of life.
  • To underscore the need for early diagnosis to enable appropriate valganciclovir treatment for affected infants, aiming to improve their health outcomes.

Main Methods:

  • The abstract does not detail specific methods but discusses the importance of diagnosis and treatment timing.
  • It emphasizes clinical recognition of congenital CMV features by specialists.
  • It calls for further research into screening, outcomes, and treatment.

Main Results:

  • The abstract does not present study results but highlights the potential benefits of early diagnosis and treatment.
  • Valaciclovir treatment during pregnancy may reduce fetal transmission or disease severity.
  • Valganciclovir treatment in neonates can improve outcomes for infants with congenital CMV.

Conclusions:

  • Congenital CMV is a common yet under-recognized condition with significant potential for long-term infant morbidity.
  • Early diagnosis and intervention are critical for managing congenital CMV and improving infant outcomes.
  • Further research is essential to guide screening strategies, understand long-term effects, and optimize treatment protocols.