Synthesis, Cellular Uptake, and Photodynamic Activity of Oligogalactosyl Zinc(II) Phthalocyanines

Invited for this month's cover is the group of Prof. Dennis K. P. Ng at The Chinese University of Hong Kong. The cover picture shows the selective internalization of molecules of a di-galactosyl zinc(II) phthalocyanine into a cancer cell. Upon light irradiation, these molecules are excited and interact with the endogenous oxygen to generate highly reactive singlet oxygen, which oxidatively damages the cellular components, leading to cell death eventually. More information can be found in the Research Article by Dennis K. P. Ng, and co-workers.