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A 2.5D Deep Learning-Based Method for Drowning Diagnosis Using Post-Mortem Computed Tomography.

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    Diagnosing drowning via autopsy is difficult. A novel 2.5D deep learning method enhances computer-aided diagnosis (CAD) using multi-slice computed tomography (MSCT) scans, improving accuracy and identifying key drowning indicators.

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    Area of Science:

    • Forensic pathology
    • Medical imaging
    • Artificial intelligence

    Background:

    • Diagnosing drowning in autopsies is challenging due to complex pathophysiology and limited forensic radiology expertise.
    • Existing computer-aided diagnosis (CAD) systems often rely on 2D data, neglecting crucial 3D information from CT scans.
    • Traditional 3D deep learning methods demand substantial data and computational resources.

    Purpose of the Study:

    • To develop an effective computer-aided diagnosis (CAD) system for drowning detection using post-mortem multi-slice computed tomography (MSCT) data.
    • To propose a novel 2.5D deep learning approach that balances 3D data representation with computational efficiency.
    • To enhance the explainability of AI-driven diagnostic results through visualization techniques.

    Main Methods:

    • A 2.5D deep learning method was developed, converting 3D MSCT data into representative 2D images for training.
    • The 2.5D approach utilizes a data subset to capture essential case information while minimizing redundancy.
    • Gradient-weighted Class Activation Mapping (Grad-CAM) was employed for visualizing image features indicative of drowning.

    Main Results:

    • The proposed 2.5D method demonstrated superior performance in drowning diagnosis compared to conventional 2D, previous 2.5D, and 3D deep learning models.
    • Evaluation was conducted on an MSCT dataset from Tohoku University.
    • Visual assessment confirmed the method's ability to identify relevant "saliency regions" associated with drowning in CT images.

    Conclusions:

    • The developed 2.5D deep learning method offers a promising solution for improving the accuracy and efficiency of computer-aided drowning diagnosis from MSCT scans.
    • This approach effectively leverages 3D CT data while mitigating the computational burdens of traditional 3D methods.
    • Explainable AI, through visualization, aids in understanding the diagnostic basis, supporting forensic specialists.