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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Antimicrobial Stewardship Programs in Preterm Infants: Encouraging Staff Nurse Engagement

Maryam Hamidi, Mary Ann Blatz

    Neonatal Network : NN
    |November 29, 2022
    PubMed

    Insights

    Antimicrobial stewardship programs can reduce antibiotic risks in NICUs. Implementing these programs for preterm infants presents challenges for nursing staff, requiring targeted strategies.

    Area of Science:

    • Neonatal Intensive Care Unit (NICU) care
    • Infectious disease management
    • Pediatric pharmacology

    Background:

    • Antibiotics are frequently used in NICUs, increasing risks of resistance and complications.
    • Antimicrobial stewardship programs (ASPs) are effective in adult populations but challenging to implement in neonatal settings.
    • Preterm infants are particularly vulnerable to the adverse effects of antibiotic misuse.

    Purpose of the Study:

    • To review the concept of antimicrobial stewardship.
    • To outline the core elements of CDC-recommended ASPs.
    • To examine nursing implementation strategies for ASPs in NICUs, focusing on preterm infants.

    Main Methods:

    • Literature review on antimicrobial stewardship principles.
    • Examination of Centers for Disease Control and Prevention (CDC) guidelines for ASPs.
    • Analysis of strategies for nursing staff in NICU settings.

    Main Results:

    • Antibiotic misuse in NICUs is a significant concern.
    • Existing ASP models face implementation hurdles in neonatal care.
    • Specific strategies are needed for nursing engagement in NICU stewardship.

    Conclusions:

    • Effective antimicrobial stewardship in NICUs is crucial for improving preterm infant outcomes.
    • Addressing nursing-specific challenges is key to successful ASP implementation.
    • Further research and tailored interventions are needed to optimize antibiotic use in neonates.
    Keywords:
    Centers for Disease ControlNICUantimicrobial stewardshipnursespharmacologypreterm infants

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