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Does the right ventricle size influence the left ventricle size and function in children with Ebstein anomaly?

Alexander A Sokolov1, Oleg A Egunov2, Evgeny V Krivoshchekov2

  • 1Department of Functional and Laboratory Diagnostics, Cardiology Research Institute, Tomsk National Research Medical Center, Tomsk, Russia.

Echocardiography (Mount Kisco, N.Y.)
|November 29, 2022
PubMed

Insights

Children with Ebstein anomaly (EA) show altered right ventricle shape and reduced function. Myocardial performance index (MPI) effectively assesses reduced right ventricular volume in EA patients.

Area of Science:

  • Pediatric Cardiology
  • Cardiovascular Imaging
  • Congenital Heart Disease

Background:

  • Ebstein anomaly (EA) presents with diverse clinical manifestations.
  • Accurate assessment of cardiac structure and geometry is crucial for effective EA management.

Purpose of the Study:

  • To evaluate the structural and geometric characteristics of the heart in pediatric patients with Ebstein anomaly.
  • To compare cardiac function and morphology between children with EA and healthy controls.

Main Methods:

  • Retrospective analysis of echocardiography data from 2009-2020.
  • Comparison of 153 children with EA (Group 1) against 2000 healthy children (Group 2).
  • Echocardiography performed following American Society of Echocardiography guidelines, assessing chamber shape, function, and myocardial mass.

Main Results:

  • Children with EA exhibited a less spherical ventricle shape, decreased myocardial mass, and reduced ejection fraction in 34% of cases.
  • The functional (non-atrialized) right ventricular volume was reduced in EA patients, with preserved contractility in 62%.
  • Preserved right ventricular contractility correlated with higher systolic pressure within the cavity.

Conclusions:

  • Tricuspid annular plane systolic excursion (TAPSE), tissue doppler imaging (TDI) parameters like TESV and annular velocity are insufficient for assessing right ventricular contractility in EA.
  • The Myocardial Performance Index (MPI) effectively indicates a decrease in the functional right ventricular volume in patients with Ebstein anomaly.
Abstract

Keywords:
Ebstein anomalytricuspid valve

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