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Current and novel echocardiographic assessment of left ventricular systolic function in aortic stenosis-A

Peter Luke1,2, Mohammad Alkhalil2,3, Christopher Eggett1,2

  • 1School of Biomedical Science, Nutritional and Sport Sciences, Newcastle University, Newcastle upon Tyne, UK.

Echocardiography (Mount Kisco, N.Y.)
|November 30, 2022
PubMed

Insights

Aortic stenosis assessment using echocardiography is evolving. Myocardial Work offers a more reliable measure of left ventricular function than ejection fraction, accounting for afterload dependency.

Area of Science:

  • Cardiology
  • Echocardiography
  • Cardiovascular Imaging

Background:

  • Aortic stenosis (AS) significantly impacts quality of life and survival.
  • Transthoracic echocardiography (TTE) is standard for AS assessment.
  • Left ventricular ejection fraction (LVEF) has limitations in accuracy and reliability.

Purpose of the Study:

  • To review echocardiographic parameters for assessing left ventricular function in AS.
  • To evaluate the role of Myocardial Work as an advanced assessment technique.

Main Methods:

  • Review of existing literature on echocardiographic assessment of AS.
  • Comparison of LVEF, myocardial deformation imaging, and Myocardial Work.
  • Analysis of afterload dependency and clinical utility.

Main Results:

  • LVEF is unreliable due to variability and loading conditions.
  • Myocardial deformation imaging shows promise but remains afterload dependent.
  • Myocardial Work integrates deformation imaging and blood pressure for comprehensive assessment.

Conclusions:

  • Myocardial Work provides a more robust evaluation of left ventricular mechanics in AS.
  • This novel technique may overcome limitations of traditional parameters like LVEF.

Keywords:
aortic stenosisejection fractionleft ventricular functionmyocardial strainmyocardial work

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