Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

4.0K
Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...
4.0K
Endocarditis II: Clinical Features of Infective Endocarditis01:25

Endocarditis II: Clinical Features of Infective Endocarditis

21
Endocarditis can present various clinical features depending on the causative organism and the patient's underlying health conditions. Initially, the clinical features of infective endocarditis develop gradually, presenting with nonspecific symptoms that can be easily mistaken for other illnesses.General SymptomsEarly symptoms of infective endocarditis are fever, chills, weakness, malaise, fatigue, and weight loss. These symptoms reflect the systemic nature of the infection and the body's...
21
Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

82
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
82
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

85
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
85
Skin Cancer01:30

Skin Cancer

4.4K
Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...
4.4K
Papillary Dermis01:11

Papillary Dermis

3.1K
Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
Papillary Layer
The papillary layer is made of loose, areolar connective tissue, which means the collagen...
3.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A multi-omics study reveals pathway-level insights and predictive biomarkers in pediatric TB.

Clinical proteomics·2026
Same author

High-resolution metabolomic analysis of stool reveals expanded biomarkers of <i>C. difficile</i> colitis and insights into pathophysiology.

Microbiology spectrum·2026
Same author

Socioeconomic disparities in biologic persistence among patients with inflammatory bowel disease are associated with increased health care utilization.

Inflammatory bowel diseases·2026
Same author

A Multi-Omics Study Reveals Pathway-Level Insights and Predictive Biomarkers in pediatric TB.

medRxiv : the preprint server for health sciences·2026
Same author

Plasma multiomics distinguishes pulmonary tuberculosis from other respiratory infections.

medRxiv : the preprint server for health sciences·2026
Same author

Novel Genetic Locus Associated with Resistance to <i>M. tuberculosis</i> Infection: A Multi-Ancestry Genome-Wide Association Study.

medRxiv : the preprint server for health sciences·2026

Related Experiment Video

Updated: Aug 19, 2025

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

1.1K

Sweet Syndrome Imitating Cutaneous Cryptococcal Disease.

Ariel A Jordan1, Daniel S Graciaa2, Srinivasa N Gopalsamy3

  • 1Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA.

Open Forum Infectious Diseases
|November 30, 2022
PubMed
Summary

Cryptococcoid Sweet syndrome, a rare variant of neutrophilic dermatosis, presents with skin lesions and yeast-like structures on biopsy. This condition can exhibit atypical skin manifestations, requiring clinical awareness for accurate diagnosis.

Keywords:
CryptococcusSweet syndromemimicsneutrophilic dermatosis

More Related Videos

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

10.9K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from S&#233;zary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

5.6K

Related Experiment Videos

Last Updated: Aug 19, 2025

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients
05:26

Author Spotlight: Oral Candida Diagnosis to Advance Clinical Treatment Regimen for pSS Patients

Published on: March 1, 2024

1.1K
Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses
10:45

Deep Dermal Injection As a Model of Candida albicans Skin Infection for Histological Analyses

Published on: June 13, 2018

10.9K
Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from S&#233;zary Syndrome Patients for Transcriptomic Profiling
09:08

Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling

Published on: October 14, 2021

5.6K

Area of Science:

  • Dermatology
  • Histopathology

Background:

  • Sweet syndrome is a neutrophilic dermatosis.
  • Cryptococcoid Sweet syndrome is a rare histologic variant.

Observation:

  • Presents with skin lesions typical of classical Sweet syndrome.
  • Histopathology shows yeast-like structures suggestive of Cryptococcus.
  • Fungal stains and cultures are negative; myeloperoxidase staining is positive.
  • Two cases presented with atypical skin manifestations, including hemorrhagic bullae and plaques.

Findings:

  • Histologic findings can mimic fungal infections like Cryptococcus.
  • Myeloperoxidase positivity aids in differentiating from fungal infections.
  • Atypical clinical presentations can occur.

Implications:

  • Clinicians must consider this variant in differential diagnosis.
  • Awareness of uncommon clinical and histopathologic findings is crucial.
  • Accurate diagnosis relies on integrating clinical, histopathologic, and special stain findings.