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Radioactive Seed Localization for Conservative Surgery of Nonpalpable Breast Cancer: Recommendations for Technology
Hortência H J Ferreira1, Carla Daruich de Souza1, Maria Elisa C M Rostelato1
1Nuclear and Energy Research Institute, IPEN, 2242 Prof. Lineu Prestes Avenue - Butantã, São Paulo, Brazil.
International Journal of Surgery Protocols
|November 30, 2022
Summary
Radioactive seed localization (RSL) improves impalpable breast cancer surgery by providing clear guidance for lesion removal. This study outlines essential recommendations for implementing RSL programs in healthcare institutions.
Area of Science:
- Oncology
- Radiology
- Nuclear Medicine
Background:
- Radioactive seed localization (RSL) is crucial for precise excision in breast cancer conservative surgery.
- It aids surgeons in accurately locating impalpable lesions for effective treatment.
Purpose of the Study:
- To present comprehensive recommendations for RSL program implementation.
- To guide health institutions performing breast cancer surgery with intraoperative localization.
Main Methods:
- Extensive literature review covering RSL program implementation aspects.
- Analysis of key components including committees, multidisciplinary teams, and radiological safety.
Main Results:
- Detailed recommendations on forming an implementation committee and multidisciplinary team.
- Guidelines for facility licensing, professional training, and material selection for RSL.
- Emphasis on seed tracking, radiological safety (ALARA principle), procedural steps, and specimen handling.
Conclusions:
- RSL offers flexibility, allowing up to two months between seed insertion and surgical removal.
- Regular multidisciplinary meetings and follow-up sessions are vital for successful RSL program development and issue resolution.

