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Idiopathic focal calvarial thinning: A case report
Atsushi Tsukada1, Kiyoyuki Yanaka2, Hayato Takeda2
1Department of Neurosurgery, University of Tsukuba, Tsukuba, Japan.
Surgical Neurology International
|November 30, 2022
Summary
This study reports a rare case of progressive unilateral calvarial bone thinning in a 77-year-old woman. The cause remains unknown, highlighting the need for further investigation into this rare cranial deformity.
Area of Science:
- Neurology
- Orthopedics
- Pathology
Background:
- Calvarial bone thinning is a rare condition with unknown etiology.
- Gorham-Stout disease is one of the few reported causes of calvarial thinning.
Observation:
- A 77-year-old woman presented with progressive unilateral cranial deformity.
- Computed tomography revealed thinning of the right parietal bone.
- Pathological examination showed localized osteoporosis of the outer bone plate without necrosis, vascular hyperplasia, or malignancy.
Findings:
- The cause of the unilateral calvarial thinning was not identified through laboratory tests or pathological examination.
- The inner bone plate remained intact, while the outer plate showed pigmentation and deformity.
Implications:
- Understanding the cause of focal calvarial thinning is crucial for determining the necessity of surgical intervention.
- Surgical intervention may be required for brain protection and to prevent cerebrospinal fluid leakage.
- This case underscores the rarity and diagnostic challenges associated with unexplained calvarial bone thinning.

