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Risk Factors of Nonsurgical Management Failure in Pediatric Intussusception Patients With Delayed Presentation
Ahmad Ali Davar1, Manijeh Khalili2, Amin Mashhadi1
1From the Department of Radiology, School of Medicine.
Insights
Ultrasound-guided hydrostatic reduction (USGHR) failure in children with ileocolic intussusception is predicted by symptom duration, free peritoneal fluid, and entrapped fluid. These factors help anticipate reduction success in delayed presentations.
Area of Science:
- Pediatric surgery
- Radiology
- Gastroenterology
Background:
- Ileocolic intussusception is a common surgical emergency in children.
- Delayed presentation increases the risk of complications and reduction failure.
- Ultrasound-guided hydrostatic reduction (USGHR) is the preferred treatment, but predictors of failure require further investigation.
Purpose of the Study:
- To identify time-related predictors of USGHR failure in pediatric ileocolic intussusception with delayed presentation (>48 hours).
Main Methods:
- Retrospective study of 103 pediatric patients with ileocolic intussusception and symptom duration >= 48 hours.
- Comparison of patients with successful versus failed USGHR based on age, sex, symptom duration, and ultrasound findings.
- Statistical analysis using chi-squared and logistic regression tests.
Main Results:
- 47.6% of patients achieved successful USGHR.
- Symptom duration, free peritoneal fluid, entrapped fluid, invaginated segment size, and malperfusion were significant predictors of USGHR failure (P < 0.05).
- No significant association found between USGHR failure and intussusception location or lymph nodes.
Conclusions:
- Entrapped fluid, free peritoneal fluid, and longer intussuscepted segments are associated with USGHR failure.
- Identifying these predictors can help anticipate reduction outcomes in delayed presentations.
Objectives:
The present study aimed to investigate the time-related predicting factors of the ultrasound-guided hydrostatic reduction (USGHR) failure in pediatric patients with ileocolic intussusception and delayed presentation.
Methods:
The present retrospective study included pediatric patients diagnosed with ileocolic intussusception who presented to our hospital with the related symptoms started 48 hours ago or greater duration during 2018-2020. The patients with spontaneous reduction were excluded from the study. Afterward, the participants with failed and successful USGHR were compared in terms of age, sex, symptom duration, and ultrasound findings using the χ 2 and logistic regression tests.
Results:
A total of 103 children were included in the present study. The mean symptom duration was 4.13 ± 2.39 days, with a range of 2-14 days. Moreover, 47.6% of the patients had a successful reduction. In addition, there was a significant relationship between failed USGHR and the factors of symptom duration, free peritoneal fluid, entrapped fluid between intussuscepted loops, the size of the invaginated segment, and malperfusion of the intussuscepted bowel loops detected using the Doppler ultrasound ( P < 0.05). However, there was no significant relationship between failed USGHR and the factors of the primary location of intussusception and the presence of intussuscepted lymph nodes ( P > 0.05).
Conclusions:
The presence of entrapped fluid between the intussuscepted loops, free peritoneal fluid, and the length of the intussuscepted segments were all associated with USGHR failure in our study. Therefore, determining these predictors may help anticipate failure of reduction.
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