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Does pulmonary hypertension affect early-term outcomes of off-pump coronary artery bypass surgery?

Yusuf Velioglu1, Ahmet Yuksel1, Dursun Topal2

  • 1Bursa City Hospital, Department of Cardiovascular Surgery - Bursa, Turkey.

Revista Da Associacao Medica Brasileira (1992)
|November 30, 2022
PubMed

Insights

Mild pulmonary hypertension (PHT) did not significantly impact early outcomes for patients undergoing off-pump coronary artery bypass grafting (CABG). This finding is crucial for surgical risk assessment in patients with PHT undergoing CABG.

Area of Science:

  • Cardiovascular Surgery
  • Pulmonary Hypertension Research
  • Anesthesiology

Background:

  • Pulmonary hypertension (PHT) is a known risk factor in cardiac surgery.
  • The impact of mild PHT on early outcomes after off-pump coronary artery bypass grafting (CABG) remains unclear.

Purpose of the Study:

  • To investigate the effect of preoperative PHT on early mortality and morbidity in patients undergoing off-pump CABG.
  • To compare postoperative outcomes between patients with and without PHT undergoing off-pump CABG.

Main Methods:

  • Retrospective observational cohort study of 1107 patients undergoing elective first-time off-pump CABG.
  • Patients categorized into PHT (systolic pulmonary artery pressure [SPAP] >30 mmHg, n=104) and non-PHT (SPAP ≤30 mmHg, n=1003) groups.
  • Comparison of preoperative demographics, operative data, and postoperative outcomes.

Main Results:

  • The PHT group had higher median age and lower left ventricular ejection fraction.
  • A greater percentage of patients in the PHT group had chronic obstructive pulmonary disease.
  • No significant differences in early-term complications or mortality between groups, except for atrial fibrillation.

Conclusions:

  • Mild PHT (mean SPAP=38.9±8.7 mmHg) does not significantly affect early-term outcomes after off-pump CABG.
  • This study provides novel insights into the safety of off-pump CABG in patients with mild PHT.
Abstract

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