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Updated: Aug 19, 2025

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Case report: "A healthy woman with exertional dyspnea: Indication of a pacemaker or not?"
Lukas Clasen1, Jan Schmidt1, Alexandru Gabriel Bejinariu1
1Division of Cardiology, Pulmonology, and Vascular Medicine, Medical Faculty, Heinrich-Heine-University, Düsseldorf, Germany.
Abstract:
The selection of patients with chronotropic incompetence (CI) for cardiac pacing therapy remains challenging. Here, we present a case of a 40-year-old woman with severe exertional dyspnea. The exercise test revealed a blunted increase in the heart rate (HR) (maximum of 110 bpm). Her exercise capacity significantly improved under atrial stimulation at 170 bpm using a temporary pacing lead. Therefore, we implanted a rate-adaptive dual-chamber pacemaker with a blended sensor. During follow-up exercise capacity normalized, and she had no residual exertional dyspnea at 6 months. This case highlights the potential value for individual assessments of CI to identify clear indications for pacemaker implantation.
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