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Atherogenic index of plasma is an independent predictor of mitral annular calcification

Sezen Baglan Uzunget1, Kader Eliz Sahin2

  • 1Department of Cardiology, Sincan State Hospital Ankara, Ankara, Turkey. sezenbaglan@hotmail.com.

BMC Cardiovascular Disorders
|November 30, 2022
PubMed

Insights

Atherogenic Index of Plasma (AIP) is linked to mitral annular calcification (MAC). Higher AIP independently predicts the presence of MAC, suggesting a potential new marker for cardiac health.

Area of Science:

  • Cardiology
  • Biochemistry
  • Medical Diagnostics

Background:

  • Atherogenic indices are linked to various cardiac conditions.
  • Conventional risk factors are associated with mitral annular calcification (MAC).
  • Data on atherogenic indices and MAC are limited.

Purpose of the Study:

  • To investigate the relationship between MAC and atherogenic indices.
  • To determine if atherogenic indices can predict MAC.

Main Methods:

  • 741 patients (427 with MAC, 314 without) were studied.
  • MAC diagnosed via transthoracic echocardiography.
  • Atherogenic coefficient (AC), Castelli risk indices (CRI-1, CRI-2), and Atherogenic Index of Plasma (AIP) calculated from lipid profiles.

Main Results:

  • No significant differences in sex, age, diabetes, or hypertension between groups.
  • Serum triglyceride, AIP, Hs-CRP, smoking, and BMI were independently associated with MAC (p < 0.001).

Conclusions:

  • Higher AIP is related to the presence of MAC.
  • AIP independently predicts MAC.
  • Further studies on modifying these indices are warranted.
Abstract

Keywords:
Atherogenic index of plasmaAtherogenic indicesMitral annular calcification

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