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Sinonasal Inverted Papilloma: A Narrative Review
1Department of E.N.T, Government Medical College and New Civil Hospital, Surat, India.
Summary
Inverted papilloma (IP), a rare sinonasal tumor, shows Human Papilloma Virus association. Complete surgical removal, often via endoscopy, is the preferred treatment for this benign lesion.
Area of Science:
- Otolaryngology
- Head and Neck Surgery
- Pathology
Background:
- Inverted papilloma (IP) is a rare sinonasal benign neoplasm with unique characteristics.
- Its presentation and management can be challenging due to resemblance to other sinonasal pathologies.
Purpose of the Study:
- To review and summarize recent advancements in the management of sinonasal inverted papilloma.
- To integrate current literature on IP, focusing on epidemiology, histopathology, staging, and surgical treatment.
Main Methods:
- Comprehensive literature review of Google Scholar and PubMed databases.
- Keywords used: "inverted papilloma", "Schneiderian", "sinonasal", "medial maxillectomy".
- Articles published in English until May 2020 were analyzed.
Main Results:
- Established association between Human Papilloma Virus (HPV) and inverted papilloma.
- Krouse staging system is widely adopted for IP classification.
- Treatment has evolved towards aggressive surgical excision, with endoscopic techniques increasingly preferred for early-stage lesions.
Conclusions:
- Complete surgical excision is the treatment of choice for inverted papilloma, regardless of SCC association.
- Endoscopic surgery is favored for accessible lesions; open surgery is indicated for extensive or less accessible tumors.
- Post-operative patient counseling and regular follow-up are crucial to monitor for recurrence.

