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Updated: Aug 19, 2025

Screening and Identification of Small Peptides Targeting Fibroblast Growth Factor Receptor2 using a Phage Display Peptide Library
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Published on: September 30, 2019

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Targeting the FGF/FGFR axis and its co-alteration allies.

Y Uehara1, S Ikeda2, K H Kim3

  • 1Department of Precision Cancer Medicine, Center for Innovative Cancer Treatment, Tokyo Medical and Dental University, Tokyo; Department of Thoracic Oncology and Respiratory Medicine, Tokyo Metropolitan Cancer and Infectious Diseases Center, Komagome Hospital, Tokyo, Japan.

ESMO Open
|December 1, 2022
PubMed
Summary

Fibroblast growth factor (FGF)/FGF receptor (FGFR) alterations are linked to poorer cancer prognosis and often occur with co-alterations. Combination therapy targeting both cyclin and FGFR pathways shows promise for treating these malignancies.

Keywords:
FGFRcombination therapydrug resistancematched therapyprecision cancer medicinetyrosine kinase inhibitor

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