Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Metabolism01:40

Overview of Metabolism

31.7K
Living cells constantly carry out various chemical reactions which are necessary for their proper functioning. These reactions are interlinked to one another via multiple pathways. The collection of these chemical reactions is known as metabolism.
Plant Metabolism
Sunlight, the primary source of energy in plants, is first absorbed by the chlorophyll pigments present in their leaves. Plants then use this energy to carry out photosynthesis, where water is oxidized into oxygen and carbon dioxide...
31.7K
What is Metabolism?00:52

What is Metabolism?

116.6K
Overview
116.6K
Proteomics01:33

Proteomics

7.7K
A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term...
7.7K
Genomics02:02

Genomics

36.9K
Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
36.9K
Introduction to Metabolism01:30

Introduction to Metabolism

233
Metabolism encompasses all biochemical reactions in a living organism, facilitating both the breakdown and synthesis of biomolecules. These metabolic processes are categorized into catabolic and anabolic pathways, which operate in a coordinated manner to ensure energy balance and cellular function.Catabolic Pathways and Energy ReleaseCatabolic pathways involve the breakdown of complex macromolecules such as carbohydrates, lipids, and proteins into smaller structures like monosaccharides, fatty...
233

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Present and Future Options for Pharmacotherapy in Cardiovascular Disease: Hemodynamic and Mechanistic Therapeutic Targets.

Medical sciences (Basel, Switzerland)·2026
Same author

Distinct systemic metabolic signatures in premenopausal women with lipedema revealed by composite indices.

Frontiers in endocrinology·2026
Same author

Ampyrone is a direct agonist of human tyrosinase and a potential therapeutic for hypopigmentation disorders.

JCI insight·2026
Same author

Targeting melanosome pH is an effective method for the treatment of oculocutaneous albinism.

bioRxiv : the preprint server for biology·2026
Same author

Combinatorial histone modifications direct ATP-dependent chromatin remodeling by NURF to promoter-proximal nucleosomes.

Nucleic acids research·2026
Same author

Metabolomics reveals LysoPC a C17:0 (LPC 17:0) as candidate biomarker for personalized medicine in morbid obesity.

Frontiers in medicine·2026

Related Experiment Video

Updated: Aug 19, 2025

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells
08:28

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells

Published on: February 23, 2024

2.0K

Metabolomics in Cell Biology.

Zuhal Eraslan1, Marta Cascante2,3,4, Ulrich L Günther5

  • 1Department of Dermatology, Weill Cornell Medicine, New York, NY, USA.

Handbook of Experimental Pharmacology
|December 1, 2022
PubMed
Summary

Cell-based metabolomics uses Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS) to study cellular metabolism in real-time, aiding cancer research and drug mechanism discovery.

Keywords:
Cell biologyMetabolomics

More Related Videos

A Strategy for Sensitive, Large Scale Quantitative Metabolomics
14:18

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

21.0K
A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing
07:41

A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing

Published on: February 4, 2017

8.5K

Related Experiment Videos

Last Updated: Aug 19, 2025

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells
08:28

Author Spotlight: Advancing Metabolomics Analysis of Rare Hematopoietic Stem Cells

Published on: February 23, 2024

2.0K
A Strategy for Sensitive, Large Scale Quantitative Metabolomics
14:18

A Strategy for Sensitive, Large Scale Quantitative Metabolomics

Published on: May 27, 2014

21.0K
A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing
07:41

A Method for Measuring Metabolism in Sorted Subpopulations of Complex Cell Communities Using Stable Isotope Tracing

Published on: February 4, 2017

8.5K

Area of Science:

  • Biomedical research
  • Cell biology
  • Metabolomics

Background:

  • Metabolomics traditionally analyzes body fluids for small molecules.
  • Cancer research increasingly utilizes cellular models due to metabolic heterogeneity.
  • Cell-specific metabolic pathways influence drug responses.

Purpose of the Study:

  • To review cell-based metabolomics applications in cell biology.
  • To highlight technologies used for real-time metabolic analysis.
  • To provide case studies on understanding drug mechanisms.

Main Methods:

  • Utilizing Nuclear Magnetic Resonance (NMR) and Mass Spectrometry (MS).
  • Applying metabolomics to cellular models for real-time analysis.
  • Investigating metabolic regulation and drug responses in cancer cells.

Main Results:

  • Cell-based metabolomics offers unique insights into metabolic regulation.
  • Specific metabolic mechanisms are crucial for cell type-specific drug responses.
  • Real-time monitoring reveals dynamic metabolic changes.

Conclusions:

  • Cell-based metabolomics is essential for understanding complex cellular metabolism.
  • This approach advances cancer research and drug development.
  • Real-time analysis provides deeper insights into drug mechanisms.