Related Experiment Video
Updated: Aug 19, 2025

Invasive Hemodynamic Monitoring of Aortic and Pulmonary Artery Hemodynamics in a Large Animal Model of ARDS
Published on: November 26, 2018
Hemodynamic and ventilatory changes in pediatric patients with special needs: A comparative clinical study
Silvia Pérez-García1, Juan-Antonio Ruiz-Roca2, Cristobal Añez3
1DDS, MS. Assistant Professor. Department of Oral and Maxillofacial Surgery. Universitat Internacional de Catalunya, Sant Cugat del Vallés (Barcelona), Spain.
Insights
Intellectually disabled children (CSN) showed lower heart rate (HR) and bispectral index (BIS) values during dental procedures compared to healthy children (HC). Hemodynamic and ventilatory changes were similar between groups, except for HR and BIS.
Area of Science:
- Anesthesiology
- Pediatric Dentistry
- Neuroscience
Background:
- Limited data exists on hemodynamic and ventilatory changes during anesthesia in intellectually disabled children.
- Bispectral index (BIS) monitoring is crucial for assessing sedation depth.
Purpose of the Study:
- To compare hemodynamic and ventilatory changes in children with special needs (CSN) versus healthy children (HC) during dental treatment.
- To evaluate the effects of propofol and sevoflurane sedation on BIS values in these pediatric groups.
Main Methods:
- Forty pediatric patients were divided into CSN and HC groups.
- Sedation was induced using sevoflurane and propofol, with local anesthesia.
- Hemodynamic (BP, HR) and ventilatory (SaO2, RR, CO2) parameters, along with BIS, were continuously monitored.
Main Results:
- Systolic and diastolic blood pressure (BP) and respiratory rate (RR) decreased similarly in both groups.
- Heart rate (HR) and BIS values were significantly lower in the CSN group compared to the HC group (p ≤ 0.05).
Conclusions:
- Children with special needs exhibit lower HR and BIS values under sedation compared to healthy children.
- Blood pressure, oxygen saturation, and exhaled CO2 levels remain comparable between CSN and HC groups during dental procedures.
Background:
Very limited data are available on the hemodynamic and ventilatory changes during sedation and general anesthesia using bispectral index (BIS) monitoring in intellectually disabled children. The purpose was to determine the hemodynamic and ventilatory changes after propofol and sevoflurane administration in children with special needs (CSN) versus healthy children (HC) during dental treatment.
Material And Methods:
Forty pediatric patients needing dental treatment were allocated into two groups: children without systemic disease (healthy children [HC]) and mentally disabled children (children with special needs [CSN]). Sevoflurane in oxygen (100% oxygen, 5 l/min) and continuous propofol infusion (target-controlled infusion [TCI], 2 µg/ml) were used as sedative agents, and 2% lidocaine with 1:80,000 adrenaline was used as local anesthesia in both groups. Heart rate (HR), oxygen saturation (SaO2), respiratory rate (RR), exhaled carbon dioxide (CO2), blood pressure (BP) and bispectral monitoring (BIS) values were recorded during the entire dental treatment procedure.
Results:
A statistically significant decrease in systolic BP, diastolic BP and RR was observed, with no significant differences between the healthy and disabled groups. In contrast, the HR and BIS values were lower in the CSN group than in the healthy patients (p ≤ 0.05).
Conclusions:
Patients with special needs had lower HR and BIS values than healthy patients, while BP, SaO2 and exhaled CO2 showed similar results in both groups. Key words:Bispectral index, hemodynamic changes, ventilatory changes, pediatric patients, special needs.
Related Concept Videos
Mechanical Ventilation I: Indication and Settings
Mechanical Ventilation II: Invasive Ventilation
Negative-Pressure Ventilators
Negative-pressure ventilators create a vacuum around the chest or body to draw air into the lungs, simulating breathing. This method does not require an...
Mechanical Ventilation III: Noninvasive Ventilation
Noninvasive Positive-Pressure Ventilation...
Assessment of Ventilation I: Respiratory Rate
A Ventilation assessment is critical for monitoring a patient's health status. Respiration, one of the most accessible vital signs, provides insights into the function of numerous body systems and can indicate serious health issues, such as brainstem injuries from head trauma.
Critical Guidelines for Assessing Ventilation:
Factors Affecting Pulmonary Ventilation
Alveolar Surface Tension
The alveolar fluid lines the luminal surface of the alveoli and exerts a force called surface tension. This force is caused by the polar water molecules in the liquid being more strongly attracted to each...
Ventilatory Modes
There are three ventilatory modes: full support, partial support, and spontaneous. These are described below.
Full Support Modes
Full support modes include controlled mechanical ventilation, continuous mandatory...

