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Obstetric Care for Monkey Pox in India: What Every Clinician Should Know
1Seth G.S. Medical College and Nowrosjee Wadia Maternity Hospital, Mumbai, India.
Abstract:
Monkeypox is a contagious viral disease that spreads between animals and people. The UK government guidance described the first case of 'Monkey Pox' in 1958, when it was found only in monkeys used for research purposes. Fortunately, for a third world fast developing country like India, monkeypox does not spread easily in the population but spread by close physical contact between people, and there is limited information available about the impact on pregnancy. The virus can enter the body through broken skin, the respiratory tract, or mucous membranes (the moist inner lining of cavities and some organs in the body). The signs and symptoms of monkeypox virus infection in people who are pregnant appear similar to those in nonpregnant people. The symptoms include fever, lymphadenopathy, lethargy, pharyngitis, headache, myalgias, and rash. Rash associated with monkeypox virus infection can be found in the anogenital area (most commonly reported location in this current outbreak), trunk, arms, legs, face, and the palms and soles. The diagnostic approach to a patient with suspected monkeypox virus infection is the same for pregnant and nonpregnant people. If a patient is present with signs and symptoms of monkeypox virus infection, diagnostic testing should be considered, especially if the person has risk factors for monkeypox virus infection. There are limited data on monkeypox infection during pregnancy. It is unknown whether pregnant people are more susceptible to monkeypox virus or whether infection is more severe in pregnancy. Monkeypox virus can be transmitted to the fetus during pregnancy or to the newborn by close contact during and after birth. Adverse pregnancy outcomes, including spontaneous pregnancy loss and stillbirth, have been reported in cases of confirmed monkeypox infection during pregnancy. Preterm delivery and neonatal monkeypox infection have also been reported. Monkeypox virus can be transmitted to the fetus during pregnancy or to the newborn by close contact during and after birth. Adverse pregnancy outcomes, including spontaneous pregnancy loss and stillbirth, have been reported in cases of confirmed monkeypox infection during pregnancy. Infection control practices for the care of patients who are pregnant with monkeypox infection are the same as those for patients who are not pregnant with monkeypox infection. This includes appropriate isolation of patients with monkeypox; training for health-care personnel on maternity and newborn care units on correct adherence to infection control practices and personal protective equipment (PPE) use and handling; and ensuring sufficient and appropriate PPE supplies are positioned at all points of care. Furthermore, visitors to pregnant or postpartum patients with monkeypox should be strictly limited to those essential for the patient's care and well-being, and should have no direct contact with the patient. Use of alternative mechanisms for patient and visitor interactions, such as video-call applications, should be encouraged for any additional support. CDC also recommends pregnant, postnatal, and breastfeeding women should be prioritized for medical treatment as there is a significant risk to the baby. They also identify these groups as eligible for treatment.
Insights
Monkeypox infection during pregnancy poses risks to both mother and baby, including potential transmission to the fetus and adverse outcomes like stillbirth. Pregnant individuals should be prioritized for medical treatment and strict infection control measures are essential.
Area of Science:
- Virology
- Public Health
- Obstetrics
Background:
- Monkeypox is a contagious viral disease with limited data on its impact during pregnancy.
- Transmission occurs through close physical contact, and the virus can enter the body via broken skin, respiratory tract, or mucous membranes.
- Symptoms in pregnant individuals are similar to nonpregnant individuals, including fever, lymphadenopathy, and rash.
Discussion:
- Symptoms in pregnant individuals mirror those in non-pregnant individuals, including fever, rash, and lymphadenopathy.
- Diagnostic approaches for suspected monkeypox are consistent across all patient populations.
- Limited data exists on increased susceptibility or severity of monkeypox in pregnant individuals.
Key Insights:
- Monkeypox virus can transmit to the fetus during pregnancy or the newborn during/after birth.
- Adverse pregnancy outcomes such as spontaneous pregnancy loss and stillbirth have been reported.
- Neonatal infection and preterm delivery are potential complications.
Outlook:
- Infection control practices for pregnant patients with monkeypox are standard, emphasizing isolation and PPE use.
- Visitor access to pregnant or postpartum patients with monkeypox should be strictly limited.
- Pregnant, postnatal, and breastfeeding women should be prioritized for medical treatment due to significant risks to the infant.
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