Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Fungal Phylum Microsporidia01:28

Fungal Phylum Microsporidia

82
Microsporidia are a group of obligate intracellular fungi that were initially classified as protists but were later reclassified based on phylogenetic, molecular, and structural evidence linking them to the Chytridiomycota. These unicellular, non-motile organisms are highly specialized parasites that infect a wide range of animal hosts, including humans. They have evolved extensive genomic and metabolic reductions, making them highly dependent on their hosts for survival.Morphology and Genomic...
82
Symbiosis00:58

Symbiosis

29.7K
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
29.7K
Diversity of Protists II01:27

Diversity of Protists II

91
Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
91
Overview of Protists01:27

Overview of Protists

103
Protists are diverse eukaryotic microorganisms that lack the specialized tissues of plants and animals and the chitinous cell walls of fungi. Their early divergence within Eukarya resulted in structural, functional, and ecological diversity. They are classified into supergroups such as Archaeplastida, Excavata, Amoebozoa, Rhizaria, Alveolata, and Stramenopiles, determined through genetic analysis and structural similarities.Structural and Functional AdaptationsProtists have various adaptations...
103
Anatomy of the Intestines01:23

Anatomy of the Intestines

72.9K
Although digestion of proteins, carbohydrates, and lipids may begin in the stomach, it is completed in the intestine. The absorption of nutrients, water, and electrolytes from food and drink also occurs in the intestine. The intestines can be divided into two structurally distinct organs—the small and large intestines.
Small Intestines
The small intestine is an ~7 meter-long tube with an inner diameter of just 2.5 cm. Since most nutrients are absorbed here, the inner lining of the...
72.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Gut Microbiome in HIV Pathogenesis: Interconnections Between Dysbiosis, Immune Dysfunction, and Viral Persistence.

International journal of molecular sciences·2026
Same author

Antibacterial and Antibiofilm Potential of Thymol-Benzimidazolium-Chalcone Hybrids Against Clinical MRSA Strains: Insights from Gene Expression Profiling and Molecular Docking.

Antibiotics (Basel, Switzerland)·2026
Same author

Sex-dependent effects of zoledronic acid on learning, memory, and hippocampal cytokines in a d-galactose-induced aging model.

Physiology & behavior·2026
Same author

Seroepidemiology and Reactivation Rates of Cytomegalovirus in HIV-Positive Patients in Istanbul: A Retrospective Analysis.

Viruses·2026
Same author

Global epidemiology of HTLV: Under-reported and under-studied regions.

Northern clinics of Istanbul·2026
Same author

Stabilization strategies for anthocyanins: recent advances.

Critical reviews in food science and nutrition·2026

Related Experiment Video

Updated: Aug 19, 2025

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection
08:14

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection

Published on: October 6, 2015

10.4K

[Malaria and Gut Microbiota: Microbial Interactions in the Host].

Mehmet Demirci1, Fadile Yıldız Zeyrek2

  • 1Kırklareli University Faculty of Medicine, Department of Medical Microbiology, Kırklareli, Türkiye.

Mikrobiyoloji Bulteni
|December 2, 2022
PubMed
Summary

Malaria infection alters gut microbiota composition, impacting host immune responses and disease severity. Further research is needed to understand the Plasmodium-gut microbiota interaction in severe malaria.

More Related Videos

Preparing and Rearing Axenic Insects with Tissue Cultured Seedlings for Host-Gut Microbiota Interaction Studies of the Leaf Beetle
06:56

Preparing and Rearing Axenic Insects with Tissue Cultured Seedlings for Host-Gut Microbiota Interaction Studies of the Leaf Beetle

Published on: October 8, 2021

2.6K
Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
10:22

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Published on: December 4, 2015

9.0K

Related Experiment Videos

Last Updated: Aug 19, 2025

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection
08:14

An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection

Published on: October 6, 2015

10.4K
Preparing and Rearing Axenic Insects with Tissue Cultured Seedlings for Host-Gut Microbiota Interaction Studies of the Leaf Beetle
06:56

Preparing and Rearing Axenic Insects with Tissue Cultured Seedlings for Host-Gut Microbiota Interaction Studies of the Leaf Beetle

Published on: October 8, 2021

2.6K
Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum
10:22

Methods to Investigate the Regulatory Role of Small RNAs and Ribosomal Occupancy of Plasmodium falciparum

Published on: December 4, 2015

9.0K

Area of Science:

  • Microbiology
  • Immunology
  • Parasitology

Background:

  • Malaria remains a significant global health issue, affecting half the world's population.
  • Emerging evidence links Plasmodium infection to alterations in gut microbiota composition.
  • The host-microbiota-pathogen triangle is a critical area for understanding malaria pathogenesis.

Approach:

  • This review synthesizes findings from human and animal studies on Plasmodium-gut microbiota interactions.
  • It examines changes in gut bacterial phyla (e.g., decreased Bacteroidetes, increased Firmicutes) during Plasmodium infection.
  • The review discusses the influence of gut bacteria on host immune responses, including T cell differentiation and antibody production.

Key Points:

  • Plasmodium infection can alter gut microbiota, potentially influencing malaria risk and severity.
  • Specific gut bacteria changes correlate with host immune responses, such as Th17 cell differentiation.
  • Short-chain fatty acid-producing bacteria may play a role in modulating the immune response to malaria.

Conclusions:

  • The Plasmodium-gut microbiota interaction is crucial for understanding severe malaria immunopathogenesis.
  • Standardized clinical studies are needed to elucidate cause-consequence relationships.
  • Investigating the Anopheles midgut microbiota's effect on Plasmodium physiology warrants further attention.