Transport Form and Pathway from the Intestine to the Peripheral Tissues and the Intestinal Absorption and Metabolism

Yasuyuki Kobayashi1, Natsumi Watanabe1, Reina Hiura2

  • 1Division of Applied Life Sciences, Graduate School of Life and Environmental Sciences, Osaka Prefecture University, Sakai, Osaka 5998531, Japan.

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Factors Influencing Drug Absorption: Anatomical Parameters

Drug absorption involves the movement of drugs from the point of administration into the systemic circulation. Initially, Gastrointestinal (GI) motility propels the drug through the digestive tract and into the stomach. However, the stomach's high acidity and limited surface area restrict its role in drug absorption for most drugs. The drug then moves from the stomach to the small intestine via gastric emptying, which can be slowed by various factors, including interactions with other...
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Factors Affecting Dissolution: Drug Permeability, Stability and Stereochemistry01:20

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Mechanisms of Drug Absorption: Paracellular, Transcellular, and Vesicular Transport01:23

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