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Current pharmacological solutions for Behçet's syndrome.
Yesim Ozguler1,2, Sinem Nihal Esatoglu1,2, Gulen Hatemi1,2
1Division of Rheumatology, Department of Internal Medicine, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey.
Behçet
Area of Science:
- Rheumatology and Immunology
- Clinical Pharmacology
Background:
- Behçet's syndrome (BS) presents with diverse clinical features.
- Treatment response varies significantly among patients, necessitating personalized therapeutic strategies.
Approach:
- Comprehensive literature review of BS management up to June 2022.
- Summarized pharmacological, surgical, and interventional options for organ-specific BS management.
Key Points:
- Treatment decisions in BS must consider involved organs, disease severity, and prognostic factors.
- Tailoring immunomodulatory, immunosuppressive, and biologic agents is crucial.
- A treat-to-attack strategy is recommended for improved long-term outcomes.
Conclusions:
- Individualized treatment plans are essential for managing Behçet's syndrome.
- Current evidence supports a range of therapeutic modalities to preserve function and quality of life.
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