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Related Concept Videos

Tissue Transplantation01:24

Tissue Transplantation

469
Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

392
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
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Kidney Transplant III: Nursing Management01:16

Kidney Transplant III: Nursing Management

59
Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...
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Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

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Overview
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Kidney Transplant I: Introduction01:28

Kidney Transplant I: Introduction

36
A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...
36
Kidney Transplant II: Surgical Procedure01:26

Kidney Transplant II: Surgical Procedure

52
Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living...
52

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Related Experiment Video

Updated: Aug 19, 2025

Murine Full-thickness Skin Transplantation
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Psoriasis in the transplant population.

Nathanael C Jensen1, Jacob Robins2, Ashley M Snyder2,3

  • 1School of Medicine, University of Utah, Salt Lake City, UT, USA.

Archives of Dermatological Research
|December 2, 2022
PubMed
Summary

Transplant patients may experience psoriasis remission or new onset. Stem cell transplants show promise for treating psoriasis, while solid organ transplant effects remain unclear, warranting further research.

Keywords:
OrganPsoriasisReviewStem cellTherapyTransplant

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Area of Science:

  • Dermatology
  • Transplantation Medicine
  • Immunology

Background:

  • Solid organ and stem cell transplants are becoming more common.
  • Dermatologists increasingly manage skin conditions like psoriasis in transplant recipients.
  • Existing literature on psoriasis in transplant patients is limited, primarily case reports.

Purpose of the Study:

  • To review psoriasis remission and occurrence in solid organ and stem cell transplant recipients.
  • To explore the potential of stem cell transplantation as a treatment for psoriasis.
  • To highlight the limited understanding of de novo psoriasis post-solid organ transplant.

Main Methods:

  • Literature review focusing on case reports and existing studies.
  • Analysis of psoriasis outcomes in hematopoietic and mesenchymal stem cell transplant recipients.
  • Examination of de novo psoriasis development in solid organ transplant recipients.

Main Results:

  • Hematopoietic and mesenchymal stem cell transplants may offer therapeutic potential for psoriasis.
  • Solid organ transplant effects on psoriasis are not well-defined.
  • De novo psoriasis has been observed post-solid organ transplant, with unclear etiology.
  • Research is constrained by the limited availability of studies.

Conclusions:

  • Stem cell transplantation presents a potential avenue for psoriasis treatment in specific patient groups.
  • Further research is crucial to elucidate the relationship between solid organ transplantation and psoriasis.
  • Understanding transplant's impact on psoriasis requires dedicated investigation due to potential benefits.