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Published on: April 4, 2025
Primary versus deferred ureteroscopy for the management of obstructive anuria secondary to ureteric urolithiasis in
Mostafa AbdelRazek1, Atef Fathi2, Mostafa Mohamed2
1Department of Urology, Qena University Hospital, South Valley University, Qena, Egypt. mostafa_uro@yahoo.com.
Insights
Deferred ureteroscopy (URS) with prior stenting is more effective for pediatric obstructive anuria from ureteral stones. This approach leads to higher stone-free rates, shorter operative times, and fewer complications compared to primary URS.
Area of Science:
- Pediatric Urology
- Endourology
- Nephrology
Background:
- Obstructive anuria in children due to ureteral stones presents a significant clinical challenge.
- Ureteroscopy (URS) is a common treatment, but the optimal timing (primary vs. deferred) requires investigation.
Purpose of the Study:
- To compare the efficacy of primary URS versus deferred URS with ureteral stenting in pediatric patients with obstructive anuria secondary to ureteral urolithiasis.
Main Methods:
- A prospective randomized study involving 120 pediatric patients (≤12 years) with obstructive anuria.
- Patients were divided into two groups: primary URS (Group A) and deferred URS after ureteral stenting (Group B).
- Outcomes assessed included operative time, renal function improvement, stone-free rate, and complication rates at 1-month follow-up.
Main Results:
- Deferred URS (Group B) demonstrated a significantly higher stone-free rate (p≤0.001) and a significantly lower mean operative time (p≤0.001) compared to primary URS (Group A).
- The overall complication rate was higher in the primary URS group.
- Primary URS failed in 16.6% of patients, while stenting failure occurred in 11% of the deferred group.
Conclusions:
- Deferred ureteroscopy with prior ureteral stenting is a preferable approach for managing obstructive anuria secondary to ureteral urolithiasis in children.
- This strategy offers advantages including reduced need for ureteral dilatation, improved stone clearance, shorter procedures, and a lower complication profile.
Abstract:
To compare the role of primary and deferred ureteroscopy (URS) in the management of obstructive anuria secondary to ureteric urolithiasis in pediatric patients. This prospective randomized study included 120 children aged ≤ 12 years who presented with obstructive anuria secondary to ureteric urolithiasis between March 2019 and January 2021. The children were subdivided into group A, which included children who had undergone primary URS without pre-stenting, and group B, which included children who had undergone URS after ureteric stenting. All children were clinically compensated and sepsis-free. Patients with underlying urological structural abnormalities were excluded. The operative time, improvement of renal functions, stone-free rate, and complications were compared between the two groups. At the 1-month follow-up, urine analysis; kidney, ureter, and bladder radiography; and ultrasonography were performed. The patient characteristics of both groups did not show any significant difference. Primary URS had failed in ten children (16.6%) in group A. Moreover, failure of stenting was noted in six patients (11%) in group B. The mean operative time for group B was significantly lower than that for group A (p ≤ 0.001). The stone-free rate was significantly higher in group B (p ≤ 0.001). The rate of overall complications was higher in group A. Deferred URS is preferable over primary URS in the management of obstructive anuria secondary to ureteric urolithiasis". In children because of the lower need for ureteric dilatation, higher stone- free rate, shorter procedure time, and lower complication rate.
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