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Author Spotlight: Evaluating the Adjuvant Efficacy and Safety of Angong Niuhuang Pill in Viral Encephalitis Treatment

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Encephalitis in travellers: a prospective multicentre study.

Léa Picard¹, Alexandra Mailles^2,3, Pierre Fillâtre^3,4

¹Université Rennes 1, Service des Maladies Infectieuses et Réanimation Médicale, Centre Hospitalo-Universitaire, Rennes, France.

Journal of Travel Medicine

|December 3, 2022

Summary

This summary is machine-generated.

International travel is a key factor in diagnosing encephalitis. Arboviruses and Herpes simplex virus (HSV) are primary causes in travelers, highlighting the need for pre-travel advice and vaccination.

Keywords:

Encephalitis arbovirus herpes simplex virus prevention travellers

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Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

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Published on: September 9, 2022

Area of Science:

Neurology
Infectious Diseases
Epidemiology

Background:

Encephalitis epidemiology varies globally, making international travel a significant diagnostic consideration.
Understanding travel-related encephalitis is crucial for effective patient management.

Purpose of the Study:

To investigate the characteristics and outcomes of encephalitis in international travellers.
To identify the primary etiological agents and risk factors for encephalitis in travellers.

Main Methods:

Ancillary study of the prospective ENCEIF cohort (62 sites, 2016-2019).
Inclusion of adult encephalitis cases meeting International Encephalitis Consortium criteria.
Definition of travellers as individuals spending at least one night abroad within the last six months.

Main Results:

14% of 494 encephalitis patients were travellers, younger and less immunocompromised than non-travellers.
Arboviruses (22%) and Herpes simplex virus (HSV) (13%) were the main causes in travellers.
Risk of poor outcome was similar between travellers and non-travellers (aOR 0.80 [0.36-1.80]).

Conclusions:

Arboviruses and HSV are the leading causes of encephalitis in travellers.
Empirical treatment should include acyclovir; pre-travel advice and vaccination can reduce risk.
Travel history is essential for the diagnostic workup of encephalitis.