Related Experiment Video
Updated: Aug 19, 2025

Measuring Gene Expression in Bombarded Barley Aleurone Layers with Increased Throughput
Published on: March 30, 2018
The ameliorative effects and mechanisms of abscisic acid on learning and memory
Ping Liao1, Qing-Yun Wu2, Sen Li3
1College of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing, 400054, China; State Key Laboratory of Trauma, Burns and Combined Injury, Daping Hospital, Army Medical University, Chongqing, 400042, China.
Abstract:
Abscisic acid (ABA), a conserved hormone existing in plants and animals, not only regulates blood glucose and inflammation but also has good therapeutic effects on obesity, diabetes, atherosclerosis and inflammatory diseases in animals. Studies have shown that exogenous ABA can pass the blood-brain barrier and inhibit neuroinflammation, promote neurogenesis, enhance synaptic plasticity, improve learning, memory and cognitive ability in the central nervous system. At the same time, ABA plays a crucial role in significant improvement of Alzheimer's disease, depression, and anxiety. Here we review the previous research progress of ABA on the physiological effects and clinical application in the related diseases. By summarizing the biological functions of ABA, we aim to reveal the possible mechanisms of ameliorative function of ABA on learning and memory, to provide a theoretical basis that ABA as a novel and safe drug improves learning memory and cognitive impairment in central system diseases such as aging, neurodegenerative diseases and traumatic brain injury.
More Related Videos
Related Concept Videos
Adaptations that Reduce Water Loss
Role of Neurotransmitters in Memory
Glutamate and Synaptic Plasticity
Glutamate, the brain's main excitatory neurotransmitter, is...
Role of Amygdala in Memory
One of the...
Long-term Depression
Calcium Ion Concentration Mechanism
If over...
Higher Mental Functions of Brain: Learning and Memory
Long-term Potentiation
Hebbian LTP
LTP can occur when...

