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Paper-based optical nanosensors - A review
Forough Ghasemi1, Nafiseh Fahimi-Kashani2, Arafeh Bigdeli3
1Department of Nanotechnology, Agricultural Biotechnology Research Institute of Iran (ABRII), Agricultural Research, Education, Extension Organization (AREEO), Karaj, 3135933151, Iran.
Analytica Chimica Acta
|December 4, 2022
Summary
Paper-based nanosensors offer affordable, sensitive, and user-friendly optical detection for point-of-care applications. This review details their fabrication, signal generation, and diverse applications, highlighting future commercialization potential.
Area of Science:
- Analytical Chemistry
- Materials Science
- Biomedical Engineering
Background:
- Paper-based analytical devices (PADs) are cost-effective, portable tools for on-site testing.
- Optical sensors on paper meet ASSURED criteria for widespread use, especially in remote settings.
- Nanostructures enhance optical signal intensity and tunability for improved sensor performance.
Purpose of the Study:
- To review the fundamentals and state-of-the-art of paper-based nanosensors.
- To comprehensively discuss fabrication, signal acquisition, and interpretation of optical PADs.
- To explore application areas and future trends for commercializing nanosensor technology.
Main Methods:
- Review of existing literature on paper-based analytical devices and nanosensors.
- Analysis of nanostructure integration for optical signal generation in PADs.
- Discussion of substrate materials, fabrication techniques, and data handling.
Main Results:
- Nanostructures provide intense and tunable optical signals ideal for paper-based sensing platforms.
- Various methods exist for fabricating optical PADs, including nanostructure stabilization.
- PADs demonstrate significant potential across chemical, biochemical, and environmental sensing.
Conclusions:
- Paper-based nanosensors are highly promising for point-of-care diagnostics and field detection.
- Further development in fabrication and commercialization strategies is crucial for widespread adoption.
- Nanosensor technology integrated with PADs offers a scalable and accessible analytical solution.
