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Updated: Aug 19, 2025

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
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A 31-year-old Woman with Painful Black Palms: Thrombosis or Vasculitis?

Linyi Peng1,2,3,4, Yunyun Fei1,2,3,4

  • 1Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital (PUMCH), Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Rheumatology and Immunology Research
|December 5, 2022
PubMed

Both of vaso-occlusive incidence of antiphospholipid syndrome (APS) or vasculitis secondary to systemic lupus erythematosus (SLE) can lead to gangrene, which requiring the urgent and appropriate therapeutic approach. However, it is sometimes difficult to achieve the differential diagnosis, especially when a tissue biopsy is difficult to obtain or is clinically contraindicated. Herein we report and discuss such a female patient who suffered rare progressive gangrene of palm skin and successfully treated with aggressive anticoagulation and immunosuppressive therapy.

Keywords:
antiphospholipid syndrome syndrome (APS)systemic lupus erythematosus(SLE)thrombosistreatmentvasculitis

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