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06:08
A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
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Prostate Tuberculosis Masquerading as Prostate Carcinoma: A Rare Case Report.
Shalini Rawat1, Anurag Singh1, Akanksha Singh1
1Department of Pathology, King George's Medical University, Lucknow, IND.
Cureus
|December 5, 2022
Summary
Genitourinary tuberculosis (GUTB) can mimic prostate cancer. Early diagnosis of prostate tuberculosis requires histopathology and nucleic acid amplification testing, especially in endemic regions.
Area of Science:
- Urology
- Infectious Diseases
- Pathology
Background:
- Genitourinary tuberculosis (GUTB) is a significant extrapulmonary manifestation of tuberculosis (TB).
- Prostate involvement is a less common but critical presentation of GUTB in males.
- Early recognition is vital for effective management and preventing complications.
Observation:
- A 65-year-old male presented with obstructive lower urinary tract symptoms (LUTS) and elevated PSA, initially suspected of prostate cancer.
- Digital rectal examination revealed prostatic enlargement with a firm, nodular surface.
- Prostate biopsy showed granulomatous prostatitis with necrosis, initially suggestive of benign prostatic hyperplasia.
Findings:
- Histopathology revealed granulomatous prostatitis with necrosis.
- Nucleic acid amplification testing (NAAT) on prostate biopsy tissue confirmed *Mycobacterium tuberculosis*.
- Standard Ziehl-Neelsen stain was negative for acid-fast bacilli.
Implications:
- Prostate tuberculosis diagnosis relies heavily on histopathology and NAAT, as clinical and radiological findings are non-specific.
- A high index of suspicion for TB is crucial in patients from endemic areas presenting with LUTS and granulomatous inflammation.
- Timely diagnosis and treatment of prostate tuberculosis are essential to prevent morbidity.
Keywords:
antitubercular therapy (att)granulomatous inflammationprostateprostate carcinomatuberculosisMore Related Videos
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