Related Experiment Video
Updated: Aug 19, 2025
03:22
Local Anesthetic Thoracoscopy for Undiagnosed Pleural Effusion
Published on: November 10, 2023
802
Malignant pleural effusion: Updates in diagnosis, management and current challenges
Dinesh Narayan Addala1,2, Nikolaos I Kanellakis1,3,4, Eihab O Bedawi2,5
1Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Frontiers in Oncology
|December 5, 2022
Summary
Malignant pleural effusion (MPE) management is evolving from symptom relief to personalized care. Future strategies will focus on tailoring treatments based on cancer type and patient survival for better outcomes.
Area of Science:
- Pulmonology
- Oncology
- Thoracic Surgery
Background:
- Malignant pleural effusion (MPE) presents significant patient symptoms and healthcare costs.
- MPE management has seen advancements through large-scale randomized trials over the last decade.
- Current treatments focus on symptom management and fluid drainage, with options like talc pleurodesis and indwelling pleural catheters.
Purpose of the Study:
- To review the current evidence base for MPE diagnosis and management.
- To discuss new discoveries and emerging trends in MPE care.
- To explore future directions for personalized MPE treatment strategies.
Main Methods:
- Review of recent large-scale randomized trials in MPE management.
- Analysis of current diagnostic and therapeutic strategies.
- Synthesis of evidence on novel approaches and future research directions.
Main Results:
- Significant progress in understanding optimal diagnostic and management strategies for MPE.
- Established effectiveness of talc pleurodesis and indwelling pleural catheters.
- Recognition of the need for personalized treatment based on malignancy type and survival probability.
Conclusions:
- MPE treatment is shifting towards personalized care, moving beyond generic pathways.
- Future MPE management will integrate patient-specific factors like cancer type and prognosis.
- Continued research is essential to refine diagnostic accuracy and therapeutic efficacy for MPE.
Related Concept Videos
01:28Pleural Effusion II: Symptoms and Management
243
Pleural Effusion Overview
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
A pleural effusion is the abnormal collection of fluid between the parietal and visceral pleura layers of tissue that form the lining of the lungs and chest cavity. It can occur independently or due to surrounding parenchymal diseases, such as infection, malignancy, or inflammatory conditions.
Clinical Manifestations:
243
01:25Pleural Effusion I: Introduction
1.5K
Pleural effusion is an abnormal fluid accumulation in the pleural cavity, a narrow space between the lungs and the chest wall. It is not a disease per se but rather a symptom or indication of an underlying disease. In normal circumstances, this space contains a small amount of fluid (5 to 15 mL), a lubricant facilitating the non-frictional movement of the pleural surfaces.
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
There are two main types of pleural effusion: transudative and exudative. They are differentiated using Light's...
1.5K
01:30Pleural Disorders: Types and Brief Description
275
The pleura is a vital part of the respiratory system. It's a double-layered membrane surrounding the lungs and lining the chest cavity. The two layers of the pleura are:
275
01:27Pneumothorax-II
261
Pneumothorax is a medical condition defined by the buildup of air in the pleural space between the lungs and the chest wall. This accumulation of air can lead to partial or complete lung collapse, resulting in a range of clinical manifestations. Understanding the clinical presentation and effective management strategies is crucial for healthcare professionals in providing timely and appropriate care to individuals with pneumothorax.
Clinical Manifestations:
Clinical Manifestations:
261
01:30Pneumonia III: Complications and Assessment
348
Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
348
01:26Endoscopic Studies II: Thoracocentesis
430
Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
430