Related Experiment Video
Updated: Aug 19, 2025

Corneal Epithelial Abrasion with Ocular Burr As a Model for Cornea Wound Healing
Published on: July 10, 2018
Recalcitrant Fungal Corneal Ulcer
Dharshini Gounder1, Archana Thool1
1Ophthalmology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Medical Sciences, Wardha, IND.
Fungal keratitis, a common cause of visual impairment in India, often requires penetrating keratoplasty when medical treatment fails. Early surgical intervention is key to saving the eye and restoring vision.
Area of Science:
- Ophthalmology
- Infectious Diseases
Background:
- Infective keratitis is a leading cause of visual impairment, particularly in rural India.
- Fungal keratitis presents a poor prognosis due to delayed diagnosis and limited effective treatments.
Observation:
- A 56-year-old female presented with worsening symptoms of a fungal corneal ulcer despite two months of antifungal therapy.
- Examination revealed a descemetocele with impending corneal perforation.
Findings:
- Therapeutic penetrating keratoplasty was recommended for the fungal corneal ulcer.
- Penetrating keratoplasty effectively replaces diseased tissue, reduces infection, and restores ocular integrity.
Implications:
- Penetrating keratoplasty is crucial for refractory keratitis, impending or actual perforation.
- Timely surgical intervention before perforation or extension improves outcomes for globe salvage and vision restoration.
More Related Videos
04:48Establishing a Severe Corneal Inflammation Model in Rats Based on Corneal Epithelium Curettage Combined with Corneal Sutures
Published on: November 22, 2024
06:15Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia
Published on: August 9, 2024