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Intrarenal Injection of Escherichia coli in a Rat Model of Pyelonephritis
Published on: July 18, 2017
Massive bilateral grade IV emphysematous pyelonephritis: Case report.
Carlos Adrián Pérez Martínez1, Ixchel Guadalupe Rodríguez Barajas1, Maria Fernanda Carballar Jeréz1
1Department of Internal Medicine, Regional General Hospital Num. 72 "Lic. Vicente Santos Guajardo", Mexican Social Security Institute, Tlalnepantla de Baz, State of Mexico, Mexico.
Emphysematous pyelonephritis (EPN) is a severe kidney infection with high mortality. This case highlights a rare, lethal Grade IV EPN requiring bilateral nephrectomy in an elderly patient.
Area of Science:
- Nephrology
- Infectious Diseases
- Radiology
Background:
- Emphysematous pyelonephritis (EPN) is a severe necrotizing renal infection characterized by gas production within the renal parenchyma.
- Escherichia coli is the most common causative agent, often associated with uncontrolled diabetes mellitus, diabetic nephropathy, and obstructive uropathy.
- Abdominal CT scan is the gold standard for diagnosing EPN, while treatment strategies increasingly favor conservative approaches over nephrectomy.
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