Related Experiment Video
Updated: Aug 19, 2025
A Murine Model of Stent Implantation in the Carotid Artery for the Study of Restenosis
Published on: May 14, 2013
Influence of Stent Length on Periprocedural Outcomes After Primary Percutaneous Coronary Intervention in Patients
Yan Chen1,2, Ya-Fang Gao3, Yun-Fan Wang2
1The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, People's Republic of China.
Insights
Longer stents in ST-segment elevation myocardial infarction (STEMI) patients undergoing percutaneous coronary intervention (PCI) increase the risk of slow flow/no-reflow. However, stent length did not significantly impact in-hospital major adverse cardiovascular events (MACE).
Area of Science:
- Cardiology
- Interventional Cardiology
- Biomedical Engineering
Background:
- Percutaneous coronary intervention (PCI) is a primary treatment for ST-segment elevation myocardial infarction (STEMI).
- Stent length is a known factor associated with adverse events post-PCI, but its specific impact on STEMI patients requires further investigation.
- Understanding the relationship between stent length and periprocedural outcomes in STEMI is crucial for optimizing treatment strategies.
Purpose of the Study:
- To evaluate the influence of target vessel stent length on angiographic outcomes and in-hospital major adverse cardiovascular events (MACE) in patients with STEMI undergoing primary PCI.
- To determine if longer stents are associated with increased periprocedural complications in STEMI patients.
Main Methods:
- A retrospective observational study of 246 STEMI patients who underwent primary PCI with successful stent implantation.
- Patients were divided into two groups based on median stent length: ≤29 mm (Group A) and >29 mm (Group B).
- Outcomes assessed included slow flow/no-reflow (SF-NR) and in-hospital MACE. Multivariate logistic regression was used to analyze correlations.
Main Results:
- The incidence of SF-NR was significantly higher in the longer stent group (Group B, 36.4%) compared to the shorter stent group (Group A, 23.2%) (p=0.024).
- In-hospital MACE rates were similar between the two groups (7.2% vs 7.4%, p=0.943).
- Multivariate analysis identified stent length, stent diameter, and peak troponin I level as independent risk factors for SF-NR.
Conclusions:
- Excessive stent length is an independent risk factor for slow flow/no-reflow during primary PCI in STEMI patients.
- Stent length does not appear to significantly influence the risk of in-hospital major adverse cardiovascular events in this patient population.
Purpose:
A longer stent is associated with adverse events after percutaneous coronary intervention (PCI). However, little information is available on the relationship between stent length and periprocedural prognosis in patients with ST segment elevation myocardial infarction (STEMI). We aimed to assess the target vessel stent length influence on angiographic outcomes and in-hospital major adverse cardiovascular event (MACE) during primary PCI in patients with STEMI.
Patients And Methods:
This single-center retrospective observational study included 246 patients with STEMI admitted to the Zhejiang Provincial People's Hospital between January 2019 and December 2021, who underwent primary PCI and successful stent implantation. The exclusion criteria included left main lesion, multiple diseased vessel-stenting, bleeding disorders, contrast allergy, and incomplete data. Patients were divided into two groups based on the median stents length: group A (≤29 mm, n=125) and group B (>29mm, n=121). Periprocedural outcomes were slow flow/no-reflow (SF-NR) and in-hospital MACE, which included acute heart failure, malignant arrhythmia, cardiovascular death, non-fatal stroke, non-fatal myocardial infarction, and urgent revascularization. Multivariate logistic analyses were used to explore the correlation between stent length and SF-NR.
Results:
A total of 246 patients (82.9% males) with a mean age of 59.9±12.6 years were included in the analysis. The incidence of SF-NR was significantly higher in group B than in group A (36.4% vs 23.2%, p=0.024). However, the in-hospital MACE incidence rate was similar between the two groups (7.2% vs 7.4%, p=0.943). Multivariate logistic regression analysis showed that stent length and diameter, and peak troponin I level were independent risk factors for SF-NR.
Conclusion:
Excessive stent length is an independent risk factor for SF-NR, without any significant influence on the risk of MACE during hospitalization.
More Related Videos
05:41Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control
Published on: December 16, 2022
05:26Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
Published on: May 28, 2019
Related Concept Videos
01:30Acute Coronary Syndrome I: Introduction
01:28Acute Coronary Syndrome IV: Interprofessional Care
01:28Cardiac Catheterization I: Pre-Procedure Overview
01:27Peripheral Artery Disease III: Interprofessional Care
01:27Coronary Artery Disease V: Interprofessional Care