Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Applications Of NMR In Biology

Applications Of NMR In Biology

Nuclear magnetic resonance (NMR) spectroscopy is a very valuable analytical technique for researchers. It has been used for more than 50 years as an analytical tool. F. Bloch and E. Purcell formulated NMR in 1946 and won the 1952 Nobel Prize in Physics for their work. Biological macromolecules such as proteins, nucleic acids, lipids, and organic molecules including pharmaceutical compounds, can be studied using this versatile tool that exploits the magnetic properties of certain nuclei.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Spontaneous imbibition in cellulose: an absorption-mediated non-Lucas-Washburn phenomenon.

Journal of colloid and interface science·2025

Same author

Dynamic NMR Relaxometry as a Straightforward Measurement of Concentration Variations in Colloidal Gels.

Langmuir : the ACS journal of surfaces and colloids·2024

Same author

Unveiling moisture transport mechanisms in cellulosic materials: Vapor vs. bound water.

PNAS nexus·2024

Same author

Critical Role of Boundary Conditions in Sorption Kinetics Measurements.

Langmuir : the ACS journal of surfaces and colloids·2023

Same author

Slow spreading with a large contact angle on hygroscopic materials.

Soft matter·2023

Same author

Two-step diffusion in cellular hygroscopic (vascular plant-like) materials.

Science advances·2022

Search research articles

Related Experiment Video

Updated: Aug 19, 2025

In Situ Monitoring of Diffusion of Guest Molecules in Porous Media Using Electron Paramagnetic Resonance Imaging

In Situ Monitoring of Diffusion of Guest Molecules in Porous Media Using Electron Paramagnetic Resonance Imaging

Published on: September 2, 2016

Dynamic NMR Relaxometry as a Simple Tool for Measuring Liquid Transfers and Characterizing Surface and Structure

Benjamin Maillet¹, Rahima Sidi-Boulenouar¹, Philippe Coussot¹

¹Laboratoire Navier (Ecole des Ponts Paris Tech-Université Gustave Eiffel-CNRS), 77420Champs-sur-Marne, France.

Langmuir : the ACS Journal of Surfaces and Colloids

|December 5, 2022

Summary

Nuclear Magnetic Resonance (NMR) relaxation analysis quantifies liquid distribution and transport in porous materials. This technique reveals how liquids move through different pore sizes over time, aiding material science understanding.

More Related Videos

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

Author Spotlight: Exploring Intrinsically Disordered Protein Dynamics Through NMR Relaxation Experiments

Author Spotlight: Exploring Intrinsically Disordered Protein Dynamics Through NMR Relaxation Experiments

Published on: November 1, 2024

Related Experiment Videos

Last Updated: Aug 19, 2025

In Situ Monitoring of Diffusion of Guest Molecules in Porous Media Using Electron Paramagnetic Resonance Imaging

In Situ Monitoring of Diffusion of Guest Molecules in Porous Media Using Electron Paramagnetic Resonance Imaging

Published on: September 2, 2016

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Combining Microfluidics and Microrheology to Determine Rheological Properties of Soft Matter during Repeated Phase Transitions

Published on: April 19, 2018

Author Spotlight: Exploring Intrinsically Disordered Protein Dynamics Through NMR Relaxation Experiments

Author Spotlight: Exploring Intrinsically Disordered Protein Dynamics Through NMR Relaxation Experiments

Published on: November 1, 2024

Area of Science:

Materials Science
Physics
Chemistry

Background:

Porous media like soil, wood, and concrete are common in daily life.
Understanding liquid penetration and extraction in these materials is crucial for various applications.
Non-destructive imaging techniques like X-ray microtomography and MRI offer insights into internal processes.

Purpose of the Study:

To review a simple, powerful technique for quantitative analysis of liquid distribution in porous media.
To demonstrate how Nuclear Magnetic Resonance (NMR) relaxation analysis can track fluid transport and phase changes.
To highlight the technique's ability to differentiate liquid distribution across pore sizes and determine specific surface areas.

Main Methods:

Analysis of Nuclear Magnetic Resonance (NMR) relaxation of proton spins in liquid molecules.
Monitoring the evolution of NMR relaxation during processes like imbibition, drying, and phase change.
Applying the technique to diverse porous materials including silica glass, polymer matrices, cellulose fibers, softwood, and cement paste.

Main Results:

The technique provides direct, quantitative data on liquid distribution and its temporal variations.
It effectively distinguishes liquid distribution within different pore sizes and types.
NMR relaxation analysis can determine the specific surface area of pore classes based on molecular interactions.

Conclusions:

NMR relaxation analysis is an efficient, cost-effective method for studying fluid dynamics in porous materials.
The technique offers high temporal resolution for quantifying fluid transfers and understanding pore-scale phenomena.
This approach enhances the physical understanding of liquid transport and distribution in complex materials.