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Radial artery occlusion after transradial procedures: impact on 1-year adverse events
Andrea Pacchioni1, Gabriele Pesarini2, Jorge Sanz-Sanchez3,4,5
1Division of Cardiology, Ospedale Civile, Mirano, Venice, Italy - andreapacchioni@gmail.com.
Insights
Radial artery occlusion (RAO) after transradial procedures does not increase the risk of major adverse cardiac and cerebrovascular events. Age and coronary artery disease extension are independent predictors of adverse events.
Area of Science:
- Cardiology
- Interventional Cardiology
- Vascular Medicine
Background:
- Radial artery occlusion (RAO) is a common complication following transradial procedures.
- The prognostic implications of RAO on patient outcomes have not been well-established.
Purpose of the Study:
- To investigate the association between radial artery occlusion and major adverse cardiac and cerebrovascular events (MACCE).
- To identify independent risk factors for MACCE after transradial coronary procedures.
Main Methods:
- Prospective study of 837 patients undergoing transradial coronary procedures.
- Radial artery patency assessed at 24 hours; RAO occurred in 4.8% of patients.
- One-year follow-up using Kaplan-Meier and Cox proportional-hazards models to assess event-free survival and risk factors.
Main Results:
- At 1-year follow-up, MACCE occurred in 4.8% of patients (2 with RAO, 35 without).
- One-year survival rates were similar between groups (94.9% vs. 95%).
- Age and extent of coronary artery disease were identified as independent predictors of adverse events.
Conclusions:
- Radial artery occlusion does not appear to have a significant prognostic impact on major adverse cardiac and cerebrovascular events.
- Age and coronary artery disease extension are significant independent predictors of adverse outcomes following transradial procedures.
Background:
Radial artery occlusion after transradial procedures is a frequent iatrogenic thrombotic process. The impact on prognosis has not been investigated. This study sought to investigate whether radial artery occlusion is related to increased risk of major adverse cardiac and cerebrovascular events, defined as death, myocardial infarction, stroke and coronary revascularization.
Methods:
Eight hundred thirty-seven consecutive patients who underwent a transradial coronary procedure had patency of radial artery checked at 24 hours. Radial artery occlusion occurred in 41 over 837 patients (4.8%); 764 (91.2%) were available for planned follow-up at 1 year and were included in the analysis. Event-free survival rate between patients with and without radial artery occlusion was calculated using Kaplan-Meier estimates, and Cox proportional-hazards models were used to identify independent risk factors.
Results:
At a median 370-day follow-up (IQR: 366-375 days), adverse events occurred in 37 patients (4.8%), 2 in patients with radial artery occlusion and 35 in patients without. One-year survival rate was 94.9% vs. 95% (unadjusted HR=1.026, 95% CI: 0.24 to 4.6, P=0.9). After multivariable modeling, age and coronary artery disease extension was associated with increased risk of adverse events.
Conclusions:
Age and coronary artery disease extension were independent predictors of adverse events at follow-up. RAO had no prognostic impact.
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Pre-Procedural Preparation
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