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Updated: Aug 18, 2025

Author Spotlight: Exploring Non-Motor Symptoms in Parkinson's Disease
Published on: September 22, 2023
Constipation in Parkinson's Disease: A Systematic Review and Meta-Analysis
Lulu Yao1, Wei Liang2, Jiahao Chen3
1Department of Traditional Chinese Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China, redlu1989@163.com.
Constipation is common in early Parkinson's disease (PD) and significantly increases the risk of developing PD. This finding may aid in earlier diagnosis and treatment for improved patient outcomes.
Area of Science:
- Neurology
- Gastroenterology
- Epidemiology
Background:
- Constipation is a frequent nonmotor symptom in Parkinson's disease (PD).
- Previous research on constipation's link to PD risk has produced conflicting findings.
- Early identification of PD risk factors like constipation could improve patient quality of life.
Conclusions:
- Constipation is highly prevalent in the prodromal stage of Parkinson's disease.
- Constipation is significantly associated with an elevated risk of developing Parkinson's disease.
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