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[Polyvascular disease in patients with myocardial infarction and chronic kidney disease]

V N Karetnikova1,2, V V Kalaeva1, M V Evseeva1

  • 1Research Institute for Complex Issues of Cardiovascular Diseases.

Terapevticheskii Arkhiv
|December 6, 2022
PubMed

Insights

This study found that polyvascular disease (PolyVD) is common in patients with myocardial infarction (MI) and chronic kidney disease (CKD). Over a third of patients with MI and CKD had lower extremity artery (LEA) stenosis, indicating widespread vascular issues.

Area of Science:

  • Cardiology
  • Nephrology
  • Vascular Medicine

Context:

  • Myocardial infarction (MI) and chronic kidney disease (CKD) are significant comorbidities.
  • Polyvascular disease (PolyVD) assessment is crucial in these high-risk patients.
  • Understanding the prevalence of PolyVD in MI patients with CKD is essential for risk stratification.

Purpose:

  • To investigate the prevalence and characteristics of polyvascular disease (PolyVD) in patients experiencing ST-segment elevation myocardial infarction (STEMI) and chronic kidney disease (CKD).

Summary:

  • A study of 954 STEMI patients (age >18) included clinical data, ECG, echocardiography, and lab tests. 771 patients underwent angiography and duplex scanning. 281 patients (36.5%) had stage 1-4 CKD (eGFR <60 ml/min/1.73 m2).
  • Results show a high prevalence of PolyVD in patients with CKD.
  • Lower extremity artery (LEA) stenosis was observed in approximately half of the patients with CKD.

Impact:

  • Highlights the significant burden of PolyVD in patients with concomitant MI and CKD.
  • Informs clinical practice regarding the need for comprehensive vascular assessment in this patient population.
  • Suggests potential for improved patient outcomes through targeted interventions for PolyVD in CKD patients with MI.
Abstract

Keywords:
chronic kidney diseaseglomerular filtration ratemyocardial infarctionpolyvascular diseaserenal dysfunction

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