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[The relationship of hypertriglyceridemia and left ventricular remodeling types in patients with chronic kidney

I T Murkamilov1,2, I S Sabirov2, V V Fomin3

  • 1Akhunbaev Kyrgyz State Medical Academy.

Terapevticheskii Arkhiv
|December 6, 2022
PubMed

Insights

Hypertriglyceridemia (THG) is linked to more comorbidities in chronic kidney disease (CKD) patients. This includes higher rates of diabetes, heart disease, gout, and cerebrovascular disorders in CKD patients with THG.

Area of Science:

  • Cardiology
  • Nephrology
  • Metabolic Disorders

Context:

  • Chronic kidney disease (CKD) affects millions globally.
  • Hypertriglyceridemia (THG) is a common lipid abnormality.
  • The interplay between THG and CKD complications requires further investigation.

Purpose:

  • To investigate the association between hypertriglyceridemia (THG) and left ventricular remodeling in patients with chronic kidney disease (CKD).

Summary:

  • 152 CKD patients (stages 1-3) were analyzed: 98 without THG and 54 with THG.
  • Comprehensive assessments included anthropometry, hemodynamics, lipid profiles, uric acid, calcium, CRP, cystatin C, vascular stiffness, and echocardiography.
  • CKD patients with THG exhibited significantly higher prevalence of type 2 diabetes, coronary heart disease, gout, hypertension, and cerebrovascular disorders compared to those without THG.

Impact:

  • Findings highlight the increased comorbidity burden in CKD patients with hypertriglyceridemia.
  • This suggests THG may exacerbate cardiovascular and metabolic complications in CKD.
  • Early identification and management of THG in CKD patients could potentially mitigate adverse outcomes.
Abstract

Keywords:
chronic kidney diseasehypertriglyceridemialeft ventricular remodeling

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