MORPHOLOGICAL RESEARCH OF ADHESIONS IN PATIENTS WITH TUBOPERITONEAL INFERTILITY

The aim: To study history, clinical manifestations and histological structure of adhesions in patients with tuboperitoneal infertility.

Materials and methods: 66 women with tuboperitoneal infertility and 30 healthy women were studied. The criterion for inclusion in the study was the presence of adhesions of the 2nd and 3rd degrees by J. Hulka et al. classification. During laparoscopy adhesions were sampled. Serial histological sections after preparation were stained with hematoxylin and eosin, picrofuxin according to van Gizon and fuxelin according to Hart.

Results: The study showed that patients with tuboperitoneal infertility, unlike the control group, had surgery on the abdominal cavity and pelvic organs much more often, as well as inflammatory diseases of the reproductive organs. The majority of women in the control group had childbirth in history, whereas among the patients with infertility ectopic pregnancies and abortions prevailed. All examined women had adhesions that were confirmed during laparoscopy. The study showed that ultrasound is not an informative method to confirm this pathology. A histological study of adhesions revealed the presence of differences in their structure depending on the etiological factor (surgery or inflammation).

Conclusions: Necessary to take into account the presence or absence of a chronic inflammatory process while developing approaches for the secondary prevention of the formation of adhesions in women with tuboperitoneal infertility at the stage of postoperative rehabilitation and infertility treatment.