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Magnetic resonance based morphometric analysis of the tentorial notch
F J Arrambide-Garza1, O De-La-Garza-Castro1, L A Alvarez-Lozada1
1Human Anatomy Department, School of Medicine, Universidad Autónoma de Nuevo León, Monterrey, Nuevo León, Mexico.
Folia Morphologica
|December 6, 2022
Summary
This study used MRI to measure the tentorial notch and third cranial nerve (CN-III) in living subjects, revealing differences from cadaveric studies and improving understanding of brain herniation.
Area of Science:
- Neuroanatomy
- Radiology
- Forensic Medicine
Background:
- Tentorial notch morphology is crucial for understanding brain injury mechanisms.
- Cadaveric studies of the tentorial notch are limited by postmortem variability.
- Magnetic resonance imaging (MRI) offers a method to study the tentorial notch in living individuals.
Purpose of the Study:
- To evaluate the morphometry of the tentorial notch and the third cranial nerve (CN-III) in living subjects using MRI.
- To compare morphometric measurements between living subjects and cadaveric samples.
- To enhance the understanding of brain herniation mechanisms through detailed neuroanatomical analysis.
Main Methods:
- A retrospective cross-sectional study analyzed 60 MRI scans.
- Measurements included maximum notch width (MNW), notch length (NL), interpedunculoclival (IC) distance, apicotectal (AT) distance, and third cranial nerve (CN-III) parameters.
- Quartile distribution techniques were used for classification of tentorial notch morphology.
Main Results:
- Tentorial notch morphology was classified into eight types based on MNW and NL quartiles.
- Significant gender differences were observed in MNW and the inter-CN-III angle.
- Strong positive correlations were found between NL and AT distance, and between right and left CN-III distances.
Conclusions:
- MRI-derived CN-III distances in living subjects differ from cadaveric measurements, likely due to postmortem brain dehydration.
- Morphometric analysis of the tentorial notch and its neurovascular relations provides valuable insights into brain herniation.
- This study establishes a baseline for tentorial notch morphometry in living populations.
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