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Updated: Aug 18, 2025

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions
Published on: February 15, 2021
Disentangling the Skeins of Brain
Brian Knutson1, Tara Srirangarajan1
1Stanford University, CA.
Abstract:
Some have argued that the brain is so complex that it cannot be understood using current reductive approaches. Drawing on examples from decision neuroscience, we instead contend that combining new neuroscientific techniques with reductive approaches that consider central brain components in time and space has generated significant progress over the past 2 decades. This progress has allowed researchers to advance from the scientific goals of description and explanation to prediction and control. Resulting knowledge promises to improve human health and well-being. As an alternative to the extremes of reductive versus emergent approaches, however, we propose a middle way of "expansion." This expansionist approach promises to leverage the specific spatial localization, temporal precision, and directed connectivity of central neural components to ultimately link levels of analysis.
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