Related Experiment Video
Updated: Aug 18, 2025
Programming Stem Cells for Therapeutic Angiogenesis Using Biodegradable Polymeric Nanoparticles
Published on: September 27, 2013
Artificial genetic polymers against human pathologies
Gleb S Ivanov1,2, Vyacheslav G Tribulovich2, Nikolay B Pestov3,4,5,6
1Institute of Cytology, Tikhoretsky Ave 4, Saint Petersburg, Russia, 194064.
Abstract:
Originally discovered by Nielsen in 1991, peptide nucleic acids and other artificial genetic polymers have gained a lot of interest from the scientific community. Due to their unique biophysical features these artificial hybrid polymers are now being employed in various areas of theranostics (therapy and diagnostics). The current review provides an overview of their structure, principles of rational design, and biophysical features as well as highlights the areas of their successful implementation in biology and biomedicine. Finally, the review discusses the areas of improvement that would allow their use as a new class of therapeutics in the future.
More Related Videos
14:20Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
Published on: June 13, 2014
08:51Evaluation of Polymeric Gene Delivery Nanoparticles by Nanoparticle Tracking Analysis and High-throughput Flow Cytometry
Published on: March 1, 2013
Related Concept Videos
02:55Synthetic Biology
Golden rice
Golden rice is a genetically modified...
00:49What is Genetic Engineering?
01:20The Central Dogma
RNA is the Missing Link Between DNA and Proteins
In the early 1900s, scientists discovered that DNA stores all the information needed for cellular functions and that proteins perform most of these functions. However, the mechanisms of converting genetic information into functional proteins remained unknown for many years. Initially, it was believed that a single gene is...
01:59CRISPR
01:09Recombinant DNA
01:16In-vitro Mutagenesis