Liver Transplantation in HIV-Infected Patient

Area of Science:

• Hepatology and Immunology
• Transplant Surgery

Background:

• Liver transplantation in patients with Human Immunodeficiency Virus (HIV) coinfection is often avoided due to stigma and perceived risks.
• End-stage liver disease (ESLD) in HIV-positive individuals presents unique challenges for transplant candidacy.

Observation:

• A 58-year-old male patient with ESLD and HIV coinfection was evaluated for liver transplantation.
• The patient met specific criteria: undetectable HIV viral load, CD4+ cell count >100/ml, and no history of AIDS-specific opportunistic infections.

Findings:

• A successful living donor liver transplantation (LDLT) was performed on the patient.
• The procedure demonstrates the feasibility of LDLT in carefully selected HIV-positive patients.

Implications:

• This case supports expanding liver transplant eligibility for HIV-positive patients meeting stringent immunological and virological criteria.
• Successful LDLT in HIV coinfection can improve long-term outcomes and quality of life.
• Further research is warranted to establish comprehensive guidelines for liver transplantation in HIV-positive populations.