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Updated: Aug 18, 2025

Author Spotlight: Unlocking New Insights in fNIRS Studies - A Novel Framework for Inter-Brain Synchrony Analysis
Published on: October 6, 2023
Psychedelics and fNIRS neuroimaging: exploring new opportunities
Felix Scholkmann1,2, Franz X Vollenweider3
1University Hospital Zurich, University of Zurich, Biomedical Optics Research Laboratory, Department of Neonatology, Zurich, Switzerland.
This paper highlights the potential of functional near-infrared spectroscopy (fNIRS), an optical neuroimaging technique, for studying brain activity changes induced by psychedelic substances. It advocates for integrating fNIRS into psychedelic research to advance understanding of these effects.
Area of Science:
- Neuroscience
- Optical Imaging
- Psychopharmacology
Background:
- The resurgence of psychedelic research necessitates advanced neuroimaging tools.
- Functional near-infrared spectroscopy (fNIRS) is a rapidly progressing optical neuroimaging technique.
Purpose of the Study:
- To introduce the potential of fNIRS for optical neuroimaging in psychedelic research.
- To advocate for the integration of fNIRS into the study of psychedelic-induced brain activity changes.
Main Methods:
- This paper is a theoretical outlook and review, not an experimental study.
- It synthesizes existing knowledge on fNIRS capabilities and psychedelic effects on the brain.
Main Results:
- fNIRS offers a promising, non-invasive method for real-time monitoring of brain activity.
- The technique is well-suited to investigate the neural correlates of psychedelic experiences.
Conclusions:
- Integrating fNIRS into psychedelic research can significantly enhance our understanding of how these substances alter brain function.
- This approach can capitalize on the current momentum in both fields to yield novel insights.
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