Related Experiment Video

Updated: Aug 18, 2025

Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring
06:11

Uncontrolled Hemorrhagic Shock Modeled via Liver Laceration in Mice with Real Time Hemodynamic Monitoring

Published on: May 21, 2017

8.7K

Severe liver trauma among pediatric patients in the Japan Trauma Registry

Makoto Aoki1, Toshikazu Abe2, Shuichi Hagiwara3

  • 1Emergency Medicine, Gunma University Graduate School of Medicine, Meabashi, Gunma, Japan.

World Journal of Pediatric Surgery
|December 7, 2022
PubMed

Insights

Pediatric liver injury management in Japan heavily utilizes angioembolization (AE). Survival rates for severe pediatric liver injuries are high and comparable to other developed nations.

Area of Science:

  • Pediatric Surgery
  • Trauma Surgery
  • Hepatology

Background:

  • Limited data exists on pediatric liver injury in Japan.
  • Understanding clinical characteristics, management, and outcomes is crucial.

Purpose of the Study:

  • To evaluate the characteristics, management strategies, and outcomes of pediatric patients with liver injury in Japan.
  • To assess the effectiveness of different management approaches, including nonoperative management (NOM) and operative management (OM).

Main Methods:

  • Retrospective cohort study using the Japan Trauma Data Bank (2004-2018).
  • Classified pediatric liver injury patients into NOM, NOM with angioembolization (AE), and OM groups.
  • Analyzed in-hospital survival, disposition, hospital length of stay (LOS), and discharge to home.

Main Results:

  • 308 pediatric patients with severe liver injury (grades ≥III) were included.
  • Angioembolization (AE) was frequently used (23% overall, 27% for isolated, 22% for non-isolated liver injury).
  • In-hospital survival was high: 99% for isolated and 88% for non-isolated liver injury.

Conclusions:

  • Pediatric liver injury management in Japan is marked by high AE utilization.
  • Survival rates in Japan are comparable to those in other developed countries.
Abstract

Keywords:
pediatricsplasticsurgery

More Related Videos

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma04:20

A Saline/Bipolar Radiofrequency Energy Device As an Adjunct for Hemostasis in Solid Organ Injury/Trauma

Published on: July 28, 2020

5.3K
Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube06:12

Inducing Acute Liver Injury in Rats via Carbon Tetrachloride CCl4 Exposure Through an Orogastric Tube

Published on: April 28, 2020

11.4K

Related Concept Videos

Acute Kidney Injury III: Clinical Manifestations01:29

Acute Kidney Injury III: Clinical Manifestations

Acute Kidney Injury (AKI) progresses through distinct clinical phases: the oliguric, diuretic, and recovery phases, each marked by unique manifestations and challenges.Oliguric Phase:The oliguric phase is the initial stage of AKI, typically lasting 10 to 14 days. This phase is marked by a significant reduction in urine output, usually less than 400 mL per day, indicating decreased kidney function. Fluid retention is a prominent feature, leading to symptoms such as edema, hypertension, and...
58
Acute Kidney Injury I: Introduction01:22

Acute Kidney Injury I: Introduction

Introduction:Acute Kidney Injury (AKI) describes a swift decrease in kidney function occurring over hours to days, characterized by the kidneys' failure to remove waste products from the bloodstream. This leads to dangerous complications like metabolic acidosis, fluid overload, and electrolyte imbalances, such as hyperkalemia, which can cause life-threatening arrhythmias. AKI is common in both hospital and outpatient settings, often triggered by dehydration, sepsis, or exposure to nephrotoxic...
54
Acute Kidney Injury V: Interprofessional Care01:20

Acute Kidney Injury V: Interprofessional Care

Acute Kidney Injury (AKI) requires a collaborative healthcare approach to restore renal function and prevent complications. Essential management strategies involve monitoring fluid and electrolyte balance, adjusting medications, initiating dialysis when necessary, and providing nutritional support.Fluid and Electrolyte ManagementFluid Monitoring: Regularly monitoring body weight, central venous pressure, and urine output helps detect fluid imbalances early. Patient intake and output are...
40
Acute Kidney Injury II: Pathophysiology01:29

Acute Kidney Injury II: Pathophysiology

Acute kidney injury (AKI) causes are categorized into three primary categories based on the location of the injury: prerenal, intrarenal (or intrinsic), and postrenal causes. This classification guides clinical management and illustrates how different pathways can impair kidney function.Etiology and Pathophysiology of Acute Kidney Injury1. Prerenal causesEtiology: Prerenal Acute Kidney Injury, the most common type, occurs when reduced blood flow to the kidneys decreases filtration capacity...
49
Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

Acute Kidney Injury IV: Diagnostic Studies and Prevention

Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
53
Acute Kidney Injury VI: Nursing Management01:22

Acute Kidney Injury VI: Nursing Management

Acute Kidney Injury (AKI) results in an inability to maintain fluid, electrolyte, and acid-base balance. Effective nursing management is critical in improving patient outcomes and includes comprehensive patient assessment and targeted interventions.Comprehensive Patient AssessmentA detailed history collection is essential, focusing on any recent infections, nephrotoxic medication use, or chronic conditions such as hypertension and diabetes that may contribute to AKI. During the physical...
45